FIELD: medicine, pharmacy. SUBSTANCE: invention relates to a composition containing trans-5-chloro-2-methyl-2,3,3a, 12b- -tetrahydro-1H-dibenzo[2,3;6,7]oxepino[4,3-c]pyrrole or its pharmaceutically acceptable salt and pharmaceutically acceptable additions that can be used in sublingual or transbuccal forms. The composition can contain additionally a pharmaceutically acceptable water-soluble or water- dispersible carrier, in part, partially hydrolyzed gelatin. Invention claims the use of the indicated compound for preparing the sublingual or transbuccal pharmaceutical composition. Invention can be used for treatment of patients with different mental disorders. The claimed composition has no adverse cardiotoxic effects - postural hypertension and/or disorders in baroreceptor function. EFFECT: enhanced effectiveness of the composition, decreased cardiovascular adverse effects. 4 cl, 1 tbl, 8 ex
| Title |
Year |
Author |
Number |
| TREATMENT OF BIPOLAR DISORDERS AND ACCOMPANYING SYMPTOMS |
2005 |
- Vong Ehrik Kho Fong
- Panadzhides Dzhon
- Skhipper Zhak
|
RU2403039C2 |
| INTERMEDIATE COMPOUNDS FOR SYNTHESIS OF TRANS-5-CHLORO-2-METHYL-2,3,3a,12b-TETRAHYDRO-1H-DIBENZ[2,3:6,7]-OXEPINO[4,5-c]PYRROLE |
2006 |
- Kemperman Gerardus Jokhannes
- Van Der Linden Jakobus Jokhannes Marija
- Rider Majkl R.
|
RU2397164C2 |
| CRYSTALLINE FORM OF ASENAPINE MALEATE |
2006 |
- Kheres Gerkhardus Jokhannes
|
RU2405786C2 |
| DERIVATIVES OF BENZOXAZEPINE, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND THEIR USING AS AGONISTS OF AMPA RECEPTOR |
2002 |
- Gruv Sajmon Dzhejms Ehntoni
- Chzhang Mingtsjan
- Shakhid Mokhammad
|
RU2279434C2 |
| DERIVATIVES OF AZETHIDINE AND PYRROLIDINE |
1998 |
- Lejsen Dirk
- Viringa Jokhannes Khubertus
- Brukkamp Khristoforus Lui Ehduard
|
RU2198873C2 |
| (PYRIDO/THIENO)[f]OXAZEPINE-5-ONE DERIVATIVES, PHARMACEUTICAL COMPOSITION BASED ON THE SAME AND METHOD FOR TREATMENT OF NEUROLOGICAL DISEASES OR MENTAL DISORDERS |
2002 |
- Gruv Sajmon Dzhejms Ehntoni
- Ehdam-Uorrall Dzhulija
- Chzhang Mingtsjan
- Gilfillan Robert
|
RU2286347C2 |
| SUBSTITUTED PIPERIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION |
1998 |
- Rae Dankan Robertson
- Dzhaap Dehvid Robert
|
RU2198172C2 |
| DERIVATIVES OF PIPERIDINE AND PHARMACEUTICAL PREPARATION BASED ON THEREOF |
1997 |
- Rae Dankan Robertson
- Gibson Samuehl Dzhordzh
|
RU2183624C2 |
| STEROID COMPOUND, METHODS OF ITS SYNTHESIS, PHARMACEUTICAL COMPOSITION |
1998 |
|
RU2182153C2 |
| DERIVATIVE OF 11-(PHENYL-SUBSTITUTED)-ESTRA-4,9-DIENE, METHOD OF ITS SYNTHESIS, PHARMACEUTICAL COMPOSITION |
1996 |
|
RU2135514C1 |
