FIELD: medicine. SUBSTANCE: method involves applying immunoenzyme analysis method. Sorption is carried out in micropanel cells of immunoglobulins of G and M class. Then, solution containing the C4 component to be determined is sorbed in the presence of Guinea pig complement. The quantity of the sorbed C4 component is determined using an enzyme reaction product with specific antibodies against human C4 bound to the enzyme with covalent bonds. Guinea pig whole serum or serum having no active C4 component is used as the Guinea pig serum. EFFECT: simplified and reliable method. 2 cl, 1 tbl
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