FIELD: organic chemistry, medicine. SUBSTANCE: invention relates to use of pyridinylaminomethylidenebiphosphonic acid tetraalkyl esters for treatment of bone sicknesses, for example, bone osteolytic disease associated with malignant neoplasm, Paget's disease, primary and secondary osteoporosis and also to pharmaceutical composition and method of treatment of bone sicknesses. EFFECT: enhanced effectiveness of treatment. 7 cl, 1 dwg, 4 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHYLENE-BIS-PHOSPHONIC ACID DERIVATIVES AND A METHOD OF THEIR SYNTHESIS | 1991 |
|
RU2086556C1 |
| NEW DERIVATIVES OF BIS-PHOSPHONIC ACID AND METHOD OF THEIR SYNTHESIS | 1991 |
|
RU2079504C1 |
| DERIVATIVES OF METHYLENE-BIS-PHOSPHONIC ACID | 1990 |
|
RU2074860C1 |
| DERIVATIVES OF METHYLENE-BIS-PHOSPHONIC ACID ANHYDRIDE, METHODS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION | 1998 |
|
RU2205833C2 |
| DERIVATIVES OF METHYLENE-BIS-PHOSPHONIC ACID AMIDES AND METHODS OF THEIR SYNTHESIS | 1993 |
|
RU2100364C1 |
| MEDICINAL PREPARATION FOR TREATING OSTEONECROSIS AND FOR TREATING PATIENTS AT RISK OF OSTEONECROSIS DEVELOPMENT | 2001 |
|
RU2284821C2 |
| THIOSUBSTITUTED PYRIDINYLBISPHOSPHONIC ACIDS OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS OR ESTERS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF TREATMENT | 1993 |
|
RU2124019C1 |
| PHOSPHONATE DERIVATIVES | 2000 |
|
RU2258707C2 |
| METHOD OF PRODUCING BIPHOSPHONIC ACIDS AND THEIR SALTS | 2007 |
|
RU2425049C2 |
| SULFUR-CONTAINING PHOSPHONIC ACIDS OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS OR ESTERS AND PHARMACEUTICAL COMPOSITION BASED ON SAID | 1993 |
|
RU2136691C1 |
