MOLECULAR VECTOR FOR DELIVERING GENES TO TARGET CELLS Russian patent published in 2002 - IPC

Abstract RU 2190018 C2

FIELD: medicine; biological engineering. SUBSTANCE: molecular structure is a set of particles with recombinant DNA and gene to be delivered being disposed in its center and antibodies to target cells being spaced over its surface. The antibodies make part of spermidinepolyglucin-conjugate capable of retaining the conjugate on the negatively charged DNA owing to positive charge of spermidine taking place and of stimulating DNA molecules to penetrate into eukaryotic cells. EFFECT: enhanced effectiveness in producing means for delivering genes to target cells. 4 dwg, 6 tbl

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RU 2 190 018 C2

Authors

Sizov A.A.

Lebedev L.R.

Masycheva V.I.

Danilenko E.D.

Dates

2002-09-27—Published

2000-08-14—Filed