INACTIVATED VACCINE AGAINST CATTLE PARAINFLUENZA-3 Russian patent published in 2003 - IPC

Abstract RU 2212896 C2

FIELD: veterinary virology, biotechnology. SUBSTANCE: the suggested vaccine contains antigenous material out of "VGNKI-4" strain out of cattle PI-3 virus, aminoethylenimine, aluminum hydroxide gel, saponin and thiomersal in efficient ratios. The strain is deposited in VGNKI collection under registration name as "VGNKI-4" DEP. Virus is reproduced both in monolayer and suspension cellular VNK-21 culture. As inactivator one should apply aminoethylenimine at concentration of 0.06%. Antigenous suspension is purified against ballast admixtures by centrifuging. To prepare adsorbent-vaccine out of adjuvants one should use aluminum hydroxide gel and saponin. Vaccine in question is of high biological, antigenous and immunogenous activity. EFFECT: higher efficiency. 9 cl

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RU 2 212 896 C2

Authors

Mishchenko V.A.

Lisitsyn V.V.

Aleksanjan R.L.

Nikeshina T.B.

Zhbanova T.V.

Dates

2003-09-27Published

2001-11-08Filed