FIELD: organic chemistry, medicine, cardiology, pharmacy. SUBSTANCE: invention relates to a pharmaceutical preparation comprising inhibitor of renin-angiotensin system and an endothelin antagonist of the formula (I) 
. The preparation shows the enhanced activity in treatment of diseases of cardio-vascular system. EFFECT: valuable medicinal properties of preparation, enhanced effectiveness. 3 tbl, 2 ex
| Title |
Year |
Author |
Number |
| PHARMACEUTICAL PREPARATION |
1994 |
- Zhan-Pol' Klozel'
- Martin Klozel'
- Vol'Fgang Osterrider
|
RU2146522C1 |
| ARALKYLSUBSTITUTED IMIDAZOLES SHOWING ANTIHYPERTENSIVE ACTION, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION SHOWING INHIBITING ACTIVITY WITH RESPECT TO ANGIOTENSIN II |
1990 |
- Robert Dzhon Ardeki[Us]
- Dejvid Dzhon Karini[Us]
- Dzhon Dzhounes Vyjtatutas Danchija[Us]
- Pankras Khor-Bun Vong[Us]
|
RU2067581C1 |
| PHARMACEUTICAL COMPOSITIONS, INCLUDING NEP INHIBITORS, INHIBITORS OF SYSTEM PRODUCING ENDOGENIC ENDOTHELIUM AND DIURETICS |
2006 |
- Vitte Klaus
- Tsigler Diter
- Shtraub Mattias
- Fisher Ivan
|
RU2409366C2 |
| (-AMINO-(-HYDROXY-(-ARYLALKANOIC AMIDES AND USE THEREOF AS RENIN INHIBITORS |
2004 |
- Zell'Ner Khol'Ger
- Gross Gerkhard
- Majbaum Jurgen Klaus
- Kotten Sil'Ven
|
RU2425027C2 |
| IMIDAZOLE DERIVATIVES, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION DECREASING BLOOD PRESSURE |
1992 |
- Al'Bert Vagner[De]
- Khajnrikh Ehnglert[De]
- Khajnts-Verner Kleemann[De]
- Khermann Gerkhards[De]
- Bernvard Shel'Kens[De]
- Rajnkhard Beker[De]
- Vol'Fgang Lints[De]
|
RU2104272C1 |
| IMIDAZOLE DERIVATIVES OR THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS, METHOD OF THEIR SYNTHESIS, AGENT FOR BLOOD HYPERTENSION DECREASE AND PHARMACEUTICAL COMPOSITION FOR BLOOD PRESSURE DECREASE |
1993 |
- Kholger Khajch
- Rainer Khenning
- Adal'Bert Vagner
- Khermann Gerkhards
- Rajnkhard Beker
- Bernvard Shel'Kens
|
RU2116300C1 |
| COMPOSITION CONTAINING ANGIOTENSIN-II RECEPTOR ANTAGONIST AND EPOXYSTEROID ALDOSTERONE RECEPTOR ANTAGONIST |
1996 |
- Dzhon S. Aleksander
- Dzhozef R. Shukh
- Richard Dzh. Gorzhinski
|
RU2166330C2 |
| PHARMACEUTICAL COMPOSITIONS CONTAINING NEP-INHIBITORS, INHIBITORS OF ENDOGENOUS ENDOTHELIN-PRODUCING SYSTEM AND AT-RECEPTOR ANTAGONISTS |
2005 |
- Tsigler Diter
- Vitte Klaus
- Shtraub Mattias
- Fisher Ivan
- Tormehlen Dirk
- Khel'T'E Dagmar
|
RU2384346C2 |
| SUBSTITUTED IMIDAZOLES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND A PHARMACEUTICAL COMPOSITION |
1991 |
- Robert Dzhon Ardeki[Us]
- Dejvid Dzhon Karini[Us]
- Dzhon Dzhounes Vyjtatutas Danchija[Us]
- Pankras Khor-Bun Vong[Us]
|
RU2099330C1 |
| SUBSTITUTED DERIVATIVES OF BISPHENYL ESTER OF BUTYRIC ACID AS NEP INHIBITORS |
2019 |
- Godtfredsen, Sven Erik
- Kagan, Mark
- Liu, Yugang
- Prashad, Mahavir
- Wang, Zhaoyin
- Zhu, Saijie
- Chai, Yongshuai
|
RU2784522C2 |
