FIELD: chemistry; medicine.
SUBSTANCE: invention relates to analgesic medication based on 6,6-dimethyl-2,4-dioxo-2,3,4,5,6,7-hexahydro-1H-indole-3-spiro-2'-(3'-aroyl-4'-hydroxy-1'-o-hydroxyphenyl -5'-oxo-2',5'-dihydropyrrol), of formula: , where: R=CH2C6H5 (a), C6H5 (b), C6H4Cl-n (c).
EFFECT: medications possess increased efficiency.
1 tbl, 4 ex
Title |
Year |
Author |
Number |
METHOD FOR PREPARING 1-ALKYL-6,6-DIMETHYL-2,4-DIOXO-2,3,4,5,6,7-HEXAHYDRO-1H-INDOLE-3-SPIRO-2-( 1-ARYL-3-AROYL-4-HYDROXY-5-OXO-2,5-DIHYDROPYRROLS) |
2003 |
- Bannikova Ju.N.
- Maslivets A.N.
|
RU2238272C1 |
1-AROYLOXY-4-HYDROXY-3-OXO-1,2,3,4,4a,5,6,7,8,8a-DECAHYDROQUINOXALIN-2-SPIRO(1-o-HYDROXYPHENYL-4,5-DIOXO-2,3,4,5-TETRAHYDROPYRROLES) AND METHOD FOR THEIR PREPARING |
2007 |
- Mashevskaja Irina Vladimirovna
- Maslivets Andrej Nikolaevich
- Tikhonov Aleksej Jakovlevich
- Mazhukin Dmitrij Gennad'Evich
|
RU2320660C1 |
11,11-DIMETHYL-1-OXO-1,2,10,11-TETRAHYDROBENZO[h]PYRROLO-[2,1-a]-ISOQUINOLINE-2-SPIRO-2-(1-ARYL-3-AROYL-4-HYDROXY-5-OXO-2,5-DIHYDROPYRROLES) ELICITING ANTIBACTERIAL ACTIVITY AGAINST GRAM-POSITIVE MICROFLORA |
2005 |
- Maslivets Andrej Nikolaevich
- Bannikova Julija Nikolaevna
- Shkljaev Jurij Vladimirovich
- Rozhkova Julija Sergeevna
- Smirnova Aleksandra Sergeevna
- Aleksandrova Galina Arsent'Evna
|
RU2281286C1 |
6,6-DIMETHYL-8-OXO-5,6,8,9-TETRAHYDROBENZO[F]-PYRROLO[2,1-ALPHA]ISOQUINOLINE-9-SPIRO-2-(3-AROYL-4-HYDROXY-1-O-HYDROXYPHENYL-5-OXO-2,5-DIHYDRO-1H-PYRROLES) AND 6,6-DIMETHYL-8-OXO-5,6,8,9-TETRAHYDROBENZO[F]PYRROLO[2,1-ALPHA]ISOQUINOLINE-9-SPIRO-2-(3-BENZOYL-4-HYDROXY-1-O-HYDROXYPHENYL-5-OXO-2,5-DIHYDRIO-1H-PYRROLE) ELICITING ANALGESIC ACTIVITY AND METHOD FOR THEIR PREPARING |
2006 |
- Anikina Lada Vladimirovna
- Racheva Nadezhda L'Vovna
- Maslivets Andrej Nikolaevich
- Shkljaev Jurij Vladimirovich
|
RU2316557C1 |
ETHYL 1'-BENZYL-3,3-DIMETNYL-1,2'-DIOXO-5'-PHENYL-1'2,2',3,4,10-HEXAHYDRO-1H-SPIRO[ACRIDINE-9,3'-PYRROL]-4'-CARBOXYLATES AND SYNTHESIS METHOD THEREOF |
2008 |
- Maslivets Andrej Nikolaevich
- Silajchev Pavel Sergeevich
- Makhmudov Ramiz Ragipovich
- Dmitriev Maksim Viktorovich
- Fedorovtseva Anastasija Nikolaevna
|
RU2387651C1 |
(Z)-1'-R-6',6'-DIMETHYL-3-(PHENYL(ARYLAMINO)METHYLENE)-6',7'-DIHYDRO-3H-SPIRO[FURANE-2,3'-INDOL]-2',4,4',5(1'H,5'H)TETRAONS AND METHOD OF THEIR OBTAINING |
2008 |
- Maslivets Andrej Nikolaevich
- Silajchev Pavel Sergeevich
- Aliev Zajnutdin Gasanovich
|
RU2365592C1 |
1,1'-DIARYL-3'-AROYL-4'-HYDROXY-1H-SPIRO [INDENO[1,2-b]PYRROL-3,2'-PYRROL]-2,4,5'-(1'H)-TRIONES AND METHOD OF THEIR OBTAINING |
2011 |
- Bubnov Nikolaj Vladimirovich
- Denislamova Ekaterina Sergeevna
- Makhmudov Ramiz Ragibovich
- Maslivets Andrej Nikolaevich
|
RU2467011C1 |
3'-AROYL-1-BENZYL-4'-HYDROXY-1'-(2-HYDROXYETHYL)-6,6-DIMETHYL-6,7-DIHYDROSPIRO[INDOLO-3,2'-PYRROLE]-2,4,5'(1H,1'H,5H)-TRIONES POSSESSING ANALGESIC ACTIVITY AND A METHOD FOR THEIR PREPARATION |
2018 |
- Tretyakov Nikita Alekseevich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
- Galeev Andrej Ruslanovich
|
RU2688931C1 |
METHYL 4-ARYL-1-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-2,3-DIOXO-2,3,5,10 -TETRAHYDROBENZO[b]PYRROLO[2,3-e][1,4]DIAZEPINE-10a(1H)-CARBOXYLATES EXHIBITING ANALGESIC ACTIVITY, AND METHOD OF THEIR PREPARATION |
2022 |
- Denislamova Ekaterina Sergeevna
- Liadov Vadim Aleksandrovich
- Makrushin Dmitrii Evgenevich
- Maslivets Andrei Nikolaevich
- Malysheva Kseniia Olegovna
- Triandafilova Galina Andreevna
- Solodnikov Sergei Iurevich
|
RU2811413C1 |
METHOD OF PRODUCING 3-AMINO-8-HYDROXY-1,6-DIOXO-2,7-DIAZASPIRO[4,4]NON-3-ENE-4-CARBONITRILES |
2012 |
- Fedoseev Sergej Vladimirovich
- Ershov Oleg Vjacheslavovich
- Lipin Konstantin Vladimirovich
- Eremkin Aleksej Vladimirovich
- Kajukov Jakov Sergeevich
- Nasakin Oleg Evgen'Evich
|
RU2495040C1 |