FIELD: medicine.
SUBSTANCE: method involves exposing genotype homozygous on functionally incomplete allele t receptor gene 1,25 dihydroxy vitamin D3 (VDR) with polymerase chain reaction being used with following sequencing electrophoresis in native polyacrylamide gel to predict predisposition. Odds ratio coefficient is calculated to predict disease clinical course severity. The coefficient shows how many times is severe degenerative dystrophic knee joint lesion occurrence probability higher in patients distinguished by unfavorable clinical course.
EFFECT: prevented pathological process aggravation.
2 cl
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Authors
Dates
2005-03-27—Published
2003-02-17—Filed