FIELD: pharmacology.
SUBSTANCE: invention provides application of bacteriochlorophyll compounds for preparation of a pharmaceutical composition for photodynamic therapy of diseases, disorders and conditions associated with corneal and scleral anomalies selected from cornea thinning and sclera weakening. The invention also includes methods of photodynamic therapy for cornea thinning or sclera stretching, comprising the steps of administration of a pharmaceutical composition containing a bacteriochlorophyll compound to a subject suffering from cornea thinning or sclera stretching; and eye irradiation with light at a wavelength in the red or near infrared region of the spectrum.
EFFECT: invention allows preparation of alternative photosensibilizer that can provide collagen cross-linking in the vast posterior sclera regions with maximum safety in relation to the retina and orbital tissues.
16 cl, 18 dwg, 2 tbl, 16 ex
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