WATER-SOLUBLE ANION-CONTAINING BACTERIOCHLOROPHYLL DERIVATIVES OF AND THEIR APPLICATION Russian patent published in 2009 - IPC C07K2/00 C07D487/22 C07D487/18 C12P17/18 A61K31/40 A61K31/555 

Abstract RU 2353624 C2

FIELD: chemistry, biochemistry.

SUBSTANCE: invention relates to field of biotechnology, namely to bacteriochlorophyll derivatives and can be used for medical and diagnostic purposes. Anion-containing water-soluble tetracyclic and pentacyclic bacteriochlorophyll (Bchl) derivatives contain one, two or three negatively charged groups and/or acid groups, which transform into negatively charged groups at physiological pH. Obtained derivatives are used for photodynamic therapy and for tumor diagnostics, as well as for killing cells or infectious agents.

EFFECT: increasing selectivity of binding with target in photodynamic therapy and diagnostics.

25 cl, 34 dwg, 5 tbl, 57 ex

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Authors

Sherts Avigdor

Brehndis Aleksandr

Mazor Okhad

Salomon Joram

Sheer Khugo

Dates

2009-04-27Published

2003-11-17Filed