FIELD: organic chemistry, chemical technology.
SUBSTANCE: derivative of quinoline carboxaldehyde i. e. 2-cyclopropyl-4-(4'-fluorophenyl)quinoline 3-carboxaldehyde is prepared by interaction of 3-cyclopropyl-3-oxopropane nitrile with 2-amino-4'-fluorobenzophenone to yield 2-cyclopropyl-4-(4'-fluorophenyl)quinoline 3-carbonitrile followed by its reduction.
EFFECT: enhanced yield of end product, simplified process.
8 cl, 11 ex
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Authors
Dates
2005-11-20—Published
2002-02-14—Filed