FIELD: medicine, pharmaceuticals.
SUBSTANCE: invention relates to new application method for adamantine derivative, namely (3-hydroxy-1-adamantyl-)-1-ethylamine hydrochloride of formula I 
as inhibitor of 1-type herpes simplex virus reproduction. Said derivative is useful in inhibition of both sensitive and resistant to main antiherpes pharmaceuticals (e.g. acyclovir) virus strains. Substance of present invention has activity by 10-times higher than tromantadin and by 5-times higher than etmantin.
EFFECT: new antiherpes drug.
2 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| (3-R-1-ADAMANTYL)-1-ETHYLAMINE HYDROCHLORIDES SHOWING ANTIVIRAL ACTIVITY AND A METHOD FOR PREPARATION THEREOF | 2001 |
|
RU2247714C2 |
| DIMERIC DERIVATIVE OF NETROPSIN - 15-LYS-BIS-NETROPSIN AND COMBINATIONS BASED ON THEREOF POSSESSING ANTI-HERPETIC ACTIVITY | 2004 |
|
RU2265610C1 |
| 2-AMINO-5,6-DIFLUOR-1-(BETA-D-RIBOFURANOSYL)-BENZIMIDAZOLE, METHOD FOR PRODUCTION AND ANTIVIRAL ACTIVITY IN TERMS OF HERPES SIMPLEX VIRUS TYPE I | 2016 |
|
RU2629670C2 |
| COMBINATIONS BASED ON NETROPSIN OR ITS BIS-DERIVATIVE ELICITING ANTI-HERPETIC ACTIVITY | 2002 |
|
RU2240792C2 |
| NETROPSIN DERIVATIVES HAVING ANTIVIRAL ACTIVITY | 2008 |
|
RU2394838C2 |
| ADAMANTYLAMIDES OF SULFUR-CONTAINING ACIDS AND THEIR ANTI-INFLUENZA ACTIVITY | 2015 |
|
RU2617850C1 |
| -4-[6-(PURINE-6-YLAMINO)HEXANOYL]-3,4-DIHYDRO-3-METHYL-7,8-DIFLUOR-2H-[1,4]BENZOXAZINE AND (3R)-4-[6-(PURINE-6-YLAMINO)HEXANOYL]-3,4-DIHYDRO-3-METHYL-7,8-DIFLUOR-2H-[1,4]BENZOXAZINE WITH ANTIVIRAL ACTIVITY | 2016 |
|
RU2644351C1 |
| 1-(1-ADAMANTYL)ETHYLAMINE DERIVATIVES AND THEIR ANTIVIRAL ACTIVITY | 2011 |
|
RU2461544C1 |
| 3-BUTYLTHIO-1-(BETA-D-2-DEOXYRIBOFURANOSYL)-5-PHENYL-(4H)-1,2,4-TRIAZOLE, SYNTHESIS, ANTI-HERPES VIRUS ACTION | 2023 |
|
RU2815137C1 |
| 2-QUINALDICARBOXYLIC ACID DERIVATIVES AND THEIR ANTI-INFLUENZA ACTIVITY | 2015 |
|
RU2624906C2 |
