METHOD FOR CORRECTING ENDOTHELIAL DYSFUNCTION Russian patent published in 2006 - IPC A61K31/198 A61K31/401 A61P9/08 G09B23/28 

Abstract RU 2271202 C1

FIELD: medicine, experimental cardiopharmacology.

SUBSTANCE: in an experiment one should intragastrically introduce APP inhibitor analapryl for laboratory animal at endothelial dysfunction, at the background of its modeling, at the dosage of 0.5 mg/kg and intraperitoneally - L-arginine at the dosage of 200 mg/kg once daily. This enables to activate correction of endothelial dysfunction due to enhancing enzymatic NO formation, L-carnitine being its donator.

EFFECT: higher efficiency of correction.

1 ex, 2 tbl

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RU 2 271 202 C1

Authors

Pokrovskij Mikhail Vladimirovich

Pokrovskaja Tat'Jana Grigor'Evna

Kochkarov Vladimir Iskhakovich

Artjushkova Elena Borisovna

Danilenko Ljudmila Mikhajlovna

Gladchenko Mikhail Petrovich

Zaloznykh Jana Igorevna

Lazarenko Galina Stepanovna

Prikhod'Ko Valerija Vasil'Evna

Pashin Evgenij Nikolaevich

Zheleznova Zinaida Tikhonovna

Prusachenko Vladimir Konstantinovich

Novikov Oleg Olegovich

Novikova Marina Jur'Evna

Dates

2006-03-10Published

2005-05-04Filed