FIELD: organic chemistry, medicine, pharmacy.
SUBSTANCE: invention proposes derivative of 3,4-dihydroisoquinoline of the formula (I) or its nontoxic salt and a pharmaceutical agent comprising its as an active component (wherein all symbols have the same values as given in description). Compound of the formula (I) possesses agonistic effect on CB2-receptors and, therefore, it can be used for prophylaxis and/or treatment of different diseases, for example, asthma, nasal allergy, atopic dermatitis, autoimmune diseases, rheumatic arthritis, immune dysfunction, postoperative pain and carcinomatous pain.
EFFECT: valuable medicinal properties of derivatives.
14 cl, 33 tbl, 561 ex
Title | Year | Author | Number |
---|---|---|---|
DIHYDRONAPHTHALENE DERIVATIVES AND MEDICINAL AGENT COMPRISING INDICATED DERIVATIVES AS ACTIVE COMPONENT | 2001 |
|
RU2268262C2 |
SUBSTITUTED BENZOPYRANE DERIVATIVES USED AGAINST ARRHYTHMIA | 2002 |
|
RU2291867C2 |
TRICYCLIC COMPOUNDS OF BENZOPYRAN AS ANTIARRHYTHMIC AGENTS | 2005 |
|
RU2380370C2 |
METHOD OF OBTAINING DERIVATIVES OF 5,6-DIHYDROPYRROLO[2,1-a]ISOQUINOLINES, WHICH CONTAIN FUNCTIONAL GROUP IN POSITION 2 | 2015 |
|
RU2575174C1 |
INHIBITORS OF HIV INTEGRASE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEREOF | 2002 |
|
RU2284315C2 |
ETHYLENEDIAMINE DERIVATIVES AND FXa INHIBITOR AND ANTICOAGULANT COMPRISING THEREOF | 2001 |
|
RU2268259C2 |
DERIVATIVES OF INDOLE, METHOD FOR THEIR PREPARING AND THEIR APPLYING | 2001 |
|
RU2259998C2 |
PIPERIDINE COMPOUND, METHOD FOR ITS PREPARING, PHARMACEUTICAL COMPOSITION AND METHOD FOR INHIBITION OF SODIUM CHANNELS AND POTASSIUM CHANNELS | 2001 |
|
RU2259365C2 |
MACROHETEROCYCLIC NUCLEOSIDE DERIVATIVES AND ANALOGUES THEREOF, PRODUCTION AND USE | 2017 |
|
RU2731385C1 |
CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DESTRUCTION OF ANDROGEN RECEPTORS AND USE THEREOF | 2020 |
|
RU2825000C2 |
Authors
Dates
2006-03-20—Published
2001-07-30—Filed