DERIVATIVES OF 3,4-DIHYDROISOQUINOLINE AND PHARMACEUTICAL AGENT COMPRISING ITS AS ACTIVE COMPONENT Russian patent published in 2006 - IPC C07D217/16 C07D217/24 C07D405/06 C07D409/06 C07D221/20 C07D491/107 C07D401/06 C07D413/06 A61K31/472 A61K31/4725 A61K31/473 

Abstract RU 2272030 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention proposes derivative of 3,4-dihydroisoquinoline of the formula (I) or its nontoxic salt and a pharmaceutical agent comprising its as an active component (wherein all symbols have the same values as given in description). Compound of the formula (I) possesses agonistic effect on CB2-receptors and, therefore, it can be used for prophylaxis and/or treatment of different diseases, for example, asthma, nasal allergy, atopic dermatitis, autoimmune diseases, rheumatic arthritis, immune dysfunction, postoperative pain and carcinomatous pain.

EFFECT: valuable medicinal properties of derivatives.

14 cl, 33 tbl, 561 ex

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RU 2 272 030 C2

Authors

Ogava Mikio

Takaoka Esikazu

Okhkhata Akira

Dates

2006-03-20Published

2001-07-30Filed