METHOD FOR TREATING THE CASES OF MALIGNANT SKIN TUMORS Russian patent published in 2007 - IPC A61N5/67 A61N7/02 A61K31/739 A61K31/409 A61K9/06 A61P35/00 

Abstract RU 2300403 C1

FIELD: medicine.

SUBSTANCE: method involves introducing photosensitizer, recording level of its accumulation in tumors, carrying out photodynamic therapy. Pyrogenal is introduced at a dose of 40-1000 mkg/csm2 before introducing photosensitizer into the tumor base with tumor temperature being recorded until stable tumor tissue hyperemia being achieved for 12-24 h. Then, the tumor is smeared with composition containing 3-10 mg of photosensitizer, gel "Ultramix" and 20-200 mcg of Pyrogenal. Treatment with ultrasound is applied with intensity 0.2-0.4 W/cm2, in labile continuous mode within 5-8 min. The composition is left on skin for 1-2 h. Then, photodynamic therapy session is uniformly carried out over the whole tumor area, with total number of 3-5 procedures per treatment course.

EFFECT: enhanced effectiveness of treatment; prolonged optimum photosensitizer dose being supported in tumor, sufficient for effective photodynamic therapy action.

Similar patents RU2300403C1

Title Year Author Number
METHOD FOR APPLYING PHOTODYNAMIC THERAPY IN TREATING PATIENTS HAVING MALIGNANT TUMORS 1999
  • Sokolov V.V.
  • Filonenko E.V.
  • Sukhin D.G.
RU2161053C1
METHOD FOR PHOTODYNAMIC THERAPY OF STAGE I BASAL CELL SKIN CANCER 2022
  • Belonogov Aleksandr Viktorovich
  • Ivanov Nikolai Arkadevich
  • Tolmachev Konstantin Viktorovich
  • Nebogin Sergei Andreevich
RU2826594C2
METHOD FOR APPLYING PHOTODYNAMIC THERAPY TO TREAT FOR MALIGNANT TUMORS 2004
  • Filinov Vladimir Leonidovich
  • Vorozhtsov Georgij Nikolaevich
  • Gasting Valerij Vjacheslavovich
  • Loshchenov Viktor Borisovich
  • Luk'Janets Evgenij Antonovich
  • Rjabova Anastasija Vladimirovna
  • Sdvizhkov Aleksandr Mikhajlovich
  • Sokolov Viktor Viktorovich
  • Stratonnikov Aleksandr Arkad'Evich
RU2275945C1
METHOD FOR PHOTODYNAMIC THERAPY OF LEFT TUMORS OF MICE EHRLICH CARCINOMA WITH CHLORINE SERIES PHOTO-SENSITIZER 2022
  • Abramova Olga Borisovna
  • Drozhzhina Valentina Vladimirovna
  • Kozlovtseva Ekaterina Aleksandrovna
  • Sivovolova Tatyana Petrovna
  • Ostroverkhov Petr Vasilevich
  • Grin Mikhail Aleksandrovich
  • Kirin Nikita Sergeevich
  • Ivanov Sergej Anatolevich
  • Kaprin Andrej Dmitrievich
RU2788766C2
METHOD FOR NON-ONCOLOGIC COSMETIC SKIN DEFECTS PHOTODYNAMIC THERAPY 2016
  • Kaprin Andrej Dmitrievich
  • Filonenko Elena Vyacheslavovna
  • Moskvicheva Lyudmila Ivanovna
RU2621845C2
METHOD OF PHOTODYNAMIC THERAPY 2014
  • Gamajunov Sergej Viktorovich
  • Korchagina Ksenija Sergeevna
  • Terent'Ev Igor' Georgievich
  • Karov Vladimir Aleksandrovich
  • Grebenkina Tat'Jana Viktorovna
  • Skrebtsova Regina Ravilevna
  • Shakhova Natal'Ja Mikhajlovna
  • Turchin Il'Ja Viktorovich
RU2552032C1
METHOD OF PHOTODYNAMIC THERAPY OF SUBJECTS WITH MALIGNANT TUMOURS 2010
  • Belyj Jurij Aleksandrovich
  • Kukushkin Nikolaj Il'Ich
  • Sklifas Alla Nikolaevna
  • Temnov Andrej Aleksandrovich
  • Tereshchenko Aleksandr Vladimirovich
RU2440158C2
PHOTODYNAMIC THERAPY OF MALIGNANT GROWTH IN ANIMAL 2015
  • Davydov Evgenij Vladimirovich
RU2604412C2
METHOD FOR PHOTODYNAMIC THERAPY OF RAT SURFACE SOLID CONNECTIVE TISSUE SARCOMA M-1 2021
  • Abramova Olga Borisovna
  • Churikova Tatiana Petrovna
  • Kozlovtseva Ekaterina Aleksandrovna
  • Drozhzhina Valentina Vladimirovna
  • Kaplan Mikhail Aleksandrovich
  • Ivanov Sergei Anatolevich
  • Kaprin Andrei Dmitrievich
RU2776449C1
FLUORESCENT DIAGNOSTIC TECHNIQUE AND PHOTODYNAMIC THERAPY OF SKIN CANCER 2008
  • Sokolov Dmitrij Viktorovich
  • Makhson Anatolij Nakhimovich
  • Kurakina Tat'Jana Jur'Evna
  • Vorozhtsov Georgij Nikolaevich
  • Kuz'Min Sergej Georgievich
  • Sokolov Viktor Viktorovich
RU2373976C1

RU 2 300 403 C1

Authors

Poljakov Pavel Jur'Evich

Bychenkov Oleg Aleksandrovich

Gerasimenko Marina Jur'Evna

Rogatkin Dmitrij Alekseevich

Gorkovenko Ol'Ga Borisovna

Dates

2007-06-10Published

2005-11-30Filed