METHOD FOR TREATING THE CASES OF MALIGNANT SKIN TUMORS Russian patent published in 2007 - IPC A61N5/67 A61N7/02 A61K31/739 A61K31/409 A61K9/06 A61P35/00 

Abstract RU 2300403 C1

FIELD: medicine.

SUBSTANCE: method involves introducing photosensitizer, recording level of its accumulation in tumors, carrying out photodynamic therapy. Pyrogenal is introduced at a dose of 40-1000 mkg/csm2 before introducing photosensitizer into the tumor base with tumor temperature being recorded until stable tumor tissue hyperemia being achieved for 12-24 h. Then, the tumor is smeared with composition containing 3-10 mg of photosensitizer, gel "Ultramix" and 20-200 mcg of Pyrogenal. Treatment with ultrasound is applied with intensity 0.2-0.4 W/cm2, in labile continuous mode within 5-8 min. The composition is left on skin for 1-2 h. Then, photodynamic therapy session is uniformly carried out over the whole tumor area, with total number of 3-5 procedures per treatment course.

EFFECT: enhanced effectiveness of treatment; prolonged optimum photosensitizer dose being supported in tumor, sufficient for effective photodynamic therapy action.

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RU 2 300 403 C1

Authors

Poljakov Pavel Jur'Evich

Bychenkov Oleg Aleksandrovich

Gerasimenko Marina Jur'Evna

Rogatkin Dmitrij Alekseevich

Gorkovenko Ol'Ga Borisovna

Dates

2007-06-10Published

2005-11-30Filed