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2 307 161

(13)

(51)

IPC

C12N7/00(2006-01-01)

A61K39/145(2006-01-01)

(21) (22)

Application

2005134836/13, 2005-11-09

(24)

Start date

2005-11-09

(22)

Actual filing date

2005-11-09

(45)

Published

2007-09-27

(72)

Inventor

Rudenko Larisa GeorgievnaAleksandrova Galina IbragimovnaLarionova Natal'Ja ValentinovnaKlimov Aleksandr Ivanovich

(73)

Holder

Gu Institut Ehksperimental'Noj Meditsiny" Ramn Niiehm Ramn)

INFLUENZA VIRUS STRAIN FOR LIVING INFLUENZA INTRANASAL VACCINE FOR INFANTS AND ADULTS Russian patent published in 2007 - IPC C12N7/00 A61K39/145

Abstract RU 2307161 C2

FIELD: virology, immunology.

SUBSTANCE: vaccine strain reassortant is obtained by specific epidemic virus with cold-adapted temperature-sensitive virus as attenuation donor. Strain actively multiplies in developing hen embryos at optimal temperature of 32-33°C and is characterized with cold-adaptation and temperature-sensitivity. Strain has two genes from epidemic virus encoding surface proteins (hemagglutinin and neuroaminidase) and six genes from attenuation donor encoding internal non-glycosylated proteins.

EFFECT: new strain for living influenza intranasal vaccine for infants and adults.

1 dwg, 3 tbl, 2 ex

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RU 2 307 161 C2

Authors

Rudenko Larisa Georgievna

Aleksandrova Galina Ibragimovna

Larionova Natal'Ja Valentinovna

Klimov Aleksandr Ivanovich

Dates

2007-09-27—Published

2005-11-09—Filed