AZASPIRO-COMPOUNDS FOR PAIN TREATMENT Russian patent published in 2008 - IPC C07D209/54 A61K31/40 A61P29/00 

Abstract RU 2322438 C2

FIELD: organic chemistry, medicine.

SUBSTANCE: invention relates to novel 2-azaspiro[4.6]undecan-3-thiones of the formula (I): wherein X1 and X2 represent in common =S; R1 means hydrogen atom (H); R2 means H; R3 means H, -RQ2; Z means 5-8-membered monocyclic saturated ring bound through a general C-atom with the first azaheterocyclic ring; R8 means (C1-C5)-alkylcarbonyl; Q2 means H, or its pharmaceutically acceptable salts used as an analgesic agent. This allows their using in treatment of chronic inflammatory and/or neuropathic pain.

EFFECT: valuable medicinal properties of compounds.

17 cl, 1 tbl, 1 dwg, 8 ex

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Authors

Meze Klaus

Zel'Ve Norma

Shmidt Dirk

Dates

2008-04-20Published

2003-02-27Filed