FIELD: medicine, oncology.
SUBSTANCE: invention is related to pharmaceutical composition for photodynamic treatment of malignant tumors, which contains therapeutically efficient amount of at least one of fullerene С60 derivatives from group of compounds, which have fullerene С60 molecule that is bound with one molecule of amino acid or dipeptide, or its pharmaceutically acceptable derivative, or complex of association with biocompatible synthetic polymers or biolpoimers and tetra pyrroles, or conjugate of association with amino compounds. Patented composition which includes the above mentioned compounds, allows using emission spectrum up to 1 mcm for photodynamic treatment, which in turn, enables broadening the application area of photodynamic treatment due to penetration of light with such wave length into deep tissues. The invention also relates to the method of photodynamic treatment of malignant tumors, when the patented pharmaceutical composition is applied.
EFFECT: composition has low toxicity and high accumulation selectivity in tumor tissues.
7 cl, 7 ex, 12 dwg
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Authors
Dates
2008-05-10—Published
2005-12-26—Filed