METHOD OF PREVENTION OF LESIONS CAUSED BY IODIN RADIONUCLIDES AND OPTIMISATION OF IODIN METABOLISM IN POST-PREVENTIVE PERIOD Russian patent published in 2008 - IPC A61K33/18 A61P43/00 A61K38/01 A61K31/195 A61K36/00 A61K35/66 A61K35/12 A61K38/42 

Abstract RU 2323733 C2

FIELD: medicine, veterinary.

SUBSTANCE: method implies administration of iodine-containing medicine, which contains organic iodine compound, into human or animal organism. And iodine is bound covalently with substance from the following groups: carbon acids, unsaturated lipid acids, lipids, terpens, terpenoids, isoprenes, peptides, polypeptides, amino acids, protein hydrolisates, polypeptide hydrolisates, proteins of plant and/or animal origin and/or microbiologic origin, mixture of lipids and unsaturated lipid acids, , mixture of isoprenes and terpens, mixture of isoprenes and protein hydrolisates, mixture of isoprenes and unsaturated lipid acids. At the same time, the proteins, peptides, polypeptides, amino acids, polypeptide and protein hydrolisates are taken so as iodine is bound covalently in 5 and 3 or 3 position of phenolic cycle, and amino acids and proteins don't show the hormonal thyroid activity. Single dose of medicine contains the sufficient iodine amount to provide its daily dose, which exceeds the physiologic requirement 10-1000 times.

EFFECT: method provides permanent prevention of lesions caused by radioactive iodine, by use of high dose of stable iodine isotope contained in medicine composition.

12 cl, 26 ex

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RU 2 323 733 C2

Authors

Andrejchuk Vasilij Petrovich

Andrejchuk Elena Viktorovna

Lysenko Nikolaj Petrovich

Rogozhina Larisa Vasil'Evna

Dates

2008-05-10Published

2002-09-17Filed