2,7-SUBSTITUTED INDOLES AND PHARMACEUTICAL COMPOSITION, WITH ANTAGONIST ACTIVITY TO К 5-ГТ6 RECEPTOR Russian patent published in 2008 - IPC C07D209/30 C07D401/02 A61K31/454 A61P43/00 

FIELD: chemistry.

SUBSTANCE: invention pertains to new 2,7-substituted indoles of formula: its pharmaceutical salts, where n represents 0, 1 or 2; p represents 1 or 2; R¹ represents phenyl, optionally substituted with one or two substitutes, chosen from a group, including halogen, C₁-C₁₂alkyl, halogenC₁-C₁₂alkyl; R² represents a mono-valent saturated residue, consisting of one ring, containing six ring atoms, one or two of which are nitrogen atoms, and the others are carbon atoms, optionally substituted with one or two C₁-C₁₂alkyls; R³ represents H, C₁-C₁₂alkyl. The compounds have antagonist action to the "5-ГТ6" receptor.

EFFECT: possibility of using these compounds in pharmaceutical compositions in an effective quantity.

8 cl, 2 tbl, 8 ex