POLYMORPHOUS FORM OF 3-PHENYLSULFONYL-8-PIPERASINE-1-YL-QUINOLINE Russian patent published in 2009 - IPC C07D215/40 A61K31/47 A61P25/00

Abstract RU 2355681 C2

FIELD: chemistry.

SUBSTANCE: invention concerns novel polymorphous form of 3-phenylsulfonyl -8-piperasine-1-yl-quinoline characterised by: infrared spectre with peaks at 724, 758, 777, 804, 818, 838, 856, 905, 918, 948, 1023, 1055, 1081, 1092, 1118, 1136, 1153, 1178, 1244, 1302, 1318, 1365, 1378, 1403, 1444, 1471, 1490, 1569, 1584, 1603 and 2819 cm^-1, combination scattering spectre with peaks at 159, 184, 214, 241, 285, 304, 318, 429, 545, 558, 614, 706, 724, 803, 856, 1000, 1023, 1080, 1093, 1136, 1152, 1233, 1243, 1317, 1343, 1364, 1378, 1403, 1446, 1569, 1584, 1602, 3050 and 3073 cm^-1, X-ray powder difractogram (XRPD) with calculated interplanar distances at angle values of 10.29, 11.94, 17.47, 19.55, 19.84 and 20.33° and melting point of 188°C.

EFFECT: pharmaceutical composition based on the claimed compound, and its application in central nervous system disorder treatment.

27 cl, 3 dwg, 3 ex

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RU 2 355 681 C2

Authors

Gladvin Asa Ehlizabet

Dates

2009-05-20—Published

2004-09-23—Filed