FIELD: medicine.
SUBSTANCE: invention refers to medicine, particularly to experimental cardiology and pharmacology. It implies simulation of endothelial dysfunction in Wistar albino male rats in experiment through daily intraperitoneal introduction of N-nitro-L-arginine methyl ester in a dose 25 mg/kg within 7 days. It is followed with daily intragastric introduction of Picamilonum 30 mg/kg within next 7 days.
EFFECT: method provides effective correction of endothelial dysfunction in specific simulation environment.
1 ex, 2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF LAMOTRIGINE CORRECTION OF ENDOTHELIAL DYSFUNCTION ASSOCIATED WITH L-NAME INDUCED NITROGEN OXIDE DEFICIENCY | 2008 |
|
RU2367421C1 |
| METHOD OF ACETYLSALICYLIC ACID BASED CORRECTION OF ENDOTHELIAL DYSFUNCTION IN L-NAME INDUCED NITRIC OXIDE DEFICIENCY | 2008 |
|
RU2364392C1 |
| METHOD OF CLOPIDOGREL-BASED CORRECTION OF ENDOTHELIAL DYSFUNCTION IN L-NAME INDUCED NITRIC OXIDE DEFICIENCY | 2008 |
|
RU2364394C1 |
| METHOD OF ENDOTHELIAL DYSFUNCTION CORRECTION BY COMBINATION OF TRIMETAZIDINE AND L-ARGININE IN L-NAME-INDUCED NITROGEN OXIDE DEFICIENCY | 2009 |
|
RU2421822C2 |
| METHOD FOR CORRECTION OF ENDOTHELIAL DYSFUNCTION WITH SOLVENT MIXTURE OF HOMEOPATHIC DILUTIONS OF POLYCLONAL RABBIT ANTIBODIES TO HUMAN ENDOTHELIAL NITROGEN OXIDE SYNTHASE C12, C30, C200 | 2006 |
|
RU2306953C1 |
| METHOD OF TADALAFIL-BASED CORRECTION OF ENDOTHELIAL DYSFUNCTION IN L-NAME INDUCED NITRIC OXIDE DEFICIENCY | 2008 |
|
RU2364395C1 |
| METHOD FOR RECOMBINANT ERYTHROPOIETIN CORRECTION OF ENDOTHELIAL DYSFUNCTION IN L-NAME INDUCED NITROGEN OXIDE DEFICIENCY | 2009 |
|
RU2409873C1 |
| METHOD OF CORRECTION OF ENDOTHELIAL DYSFUNCTION BY PHOSPHOGLIV PREPARATION AT L-NAME INDUCED DEFICIENCY OF NITROGEN OXIDE | 2008 |
|
RU2359668C1 |
| METHOD OF CORRECTING ENDOTHELIAL DYSFUNCTION WITH COMBINATION OF LOZARTAN AND RAZVERATROL IN CASES OF LONAME-INDUCED NITROGEN MONOXIDE DEFICIENCY | 2005 |
|
RU2306924C1 |
| METHOD FOR CORRECTION OF ENDOTHELIAL DYSFUNCTION WITH PREPARATION PHOSPHOGLIV LYOPHILIZATE IN L-NAME INDUCED NITROGEN OXIDE DEFICIENCY | 2008 |
|
RU2372078C1 |
