HETEROARYL DERIVATIVES AS ACTIVATORS OF PEROXISOME PROLIFERATOR RECEPTORS (PPAR) Russian patent published in 2009 - IPC C07D403/12 C07D401/12 C07D209/26 A61K31/404 A61K31/506 

Abstract RU 2367659 C2

FIELD: medicine.

SUBSTANCE: invention covers new compounds of formula (I) where: one of groups R6, R7 and R8 meets formula (II) and groups X, Y1-Y4, R1-R14 and n possess the values specified in the patent claim, and also their pharmaceutically acceptable salts. Compounds I show activating effect with respect to PPARδ and/or PPARαreceptors.

EFFECT: applicability of compounds for treatment and prevention of the diseases modulated by PPARδ and PPARα agonists.

22 cl, 8 dwg, 1 tbl, 21 ex

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RU 2 367 659 C2

Authors

Akkermann Zhan

Ehbi Iogannes

Bindzheli Al'Fred

Greter Uve

Irt Zhorzh

Kun Bernd

Mehrki Khans-Peter

Mejer Markus

Mor Peter

Rajt Matt'Ju Blejk

Dates

2009-09-20Published

2004-10-28Filed