THIAZOLE-SUBSTITUTED INDOLYL-DERIVATIVES AND APPLICATION THEIROF AS PPAR MODULATORS Russian patent published in 2009 - IPC C07D417/12 A61K31/427 A61P3/04 A61P3/10 

Abstract RU 2344135 C2

FIELD: chemistry.

SUBSTANCE: this invention refers to compounds of formula where one of R6, R7 or R8 means , and X, Y, substitutes of R1-R13 and n are as it is defined in item 1 of formula of invention, and to all their enantiomers, to pharmaceutically acceptable salts and/or esters.

EFFECT: production of compounds for treatment and/or prevention of diseases modulated by PPARδ and/or PPARα agonists.

26 cl, 1 tbl, 35 ex

Similar patents RU2344135C2

Title Year Author Number
PHENYL DERIVATIVES AS PPAR AGONISTS 2004
  • Akkermann Zhan
  • Ehbi Iogannes
  • Bindzheli Al'Fred
  • Greter Uve
  • Irt Zhorzh
  • Kun Bernd
  • Mehrki Khans-Peter
  • Mejer Markus
  • Mor Peter
  • Rajt Mat'Ju Blejk
RU2374230C2
PYRAZOLE- AND PHENYL DERIVATIVES AS PPAR INHIBITORS 2005
  • Akkermann Zhan
  • Ehbi Iogannes
  • Bindzheli Al'Fred
  • Greter Uve
  • Irt Zhorzh
  • Kun Bernd
  • Mehrki Khans-Peter
  • Mejer Markus
  • Mor Peter
  • Rajt Matt'Ju Blejk
RU2384573C2
HETEROARYL DERIVATIVES AS ACTIVATORS OF PEROXISOME PROLIFERATOR RECEPTORS (PPAR) 2004
  • Akkermann Zhan
  • Ehbi Iogannes
  • Bindzheli Al'Fred
  • Greter Uve
  • Irt Zhorzh
  • Kun Bernd
  • Mehrki Khans-Peter
  • Mejer Markus
  • Mor Peter
  • Rajt Matt'Ju Blejk
RU2367659C2
BENZANNEALED COMPOUNDS AS PPAR ACTIVATORS 2004
  • Akkermann Zhan
  • Ehbi Iogannes
  • Bindzheli Al'Fred
  • Greter Uve
  • Irt Zhorzh
  • Kun Bernd
  • Mehrki Khans-Peter
  • Mejer Markus
  • Mor Peter
  • Rajt Matt'Ju Blejk
RU2367654C2
PYRAZOLYL INDOLYL DERIVATIVES AS PPAR ACTIVATORS 2005
  • Akkermann Zhan
  • Ehbi Iogannes
  • Bindzheli Al'Fred
  • Greter Uve
  • Irt Zhorzh
  • Kun Bernd
  • Mehrki Khans-Peter
  • Mejer Markus
  • Mor Peter
  • Rajt Matt'Ju Blejk
RU2375357C2
(-AMINO-(-HYDROXY-(-ARYLALKANOIC AMIDES AND USE THEREOF AS RENIN INHIBITORS 2004
  • Zell'Ner Khol'Ger
  • Gross Gerkhard
  • Majbaum Jurgen Klaus
  • Kotten Sil'Ven
RU2425027C2
NOVEL COMPOUNDS OF 2-ARYLTHIAZOLE AS AGONISTS OF PPAR α AND PPAR γ 2003
  • Bindzheli Al'Fred
  • Greter Uve
  • Khil'Ert Khans
  • Irt Zhorzh
  • Mehrki Khans-Peter
  • Mejer Markus
  • Mor Peter
RU2296754C2
N-SUBSTITUTED 1H-INDOLE-5-PROPIONIC ACIDS, PHARMACEUTICAL COMPOSITION CONTAINING THESE COMPOUNDS AND THEIR USING (VARIANTS) 2003
  • Bindzheli Al'Fred
  • Greter Uve
  • Khil'Pert Khans
  • Khumm Roland
  • Iding Khans
  • Kun Bernd
  • Mehrki Khans-Peter
  • Mejer Markus
  • Mor Peter
  • Virts Beat
RU2296759C2
INDOLE DERIVATIVES CONTAINING ACETYLENE GROUP AS PPAR ACTIVATORS 2005
  • Akkermann Zhan
  • Ehbi Iogannes
  • Bindzheli Al'Fred
  • Greter Uve
  • Kun Bernd
  • Mehrki Khans-Peter
  • Mejer Markus
RU2387639C2
PHARMACEUTICAL COMBINATIONS CONTAINING PYRIDO[4,3-d]PYRIMIDINE DERIVATIVES AS HSP90 INHIBITOR AND HER2 INHIBITOR 2009
  • Karlos Garsija-Ehcheverrija
  • Mikaehl' Jensen
RU2532375C2

RU 2 344 135 C2

Authors

Akkermann Zhan

Ehbi Iogannes

Bindzheli Al'Fred

Greter Uve

Irt Zhorzh

Kun Bernd

Mehrki Khans-Peter

Mejer Markus

Mor Peter

Rajt Matt'Ju Blejk

Dates

2009-01-20Published

2004-06-25Filed