METHOD AND SYSTEM TO REMOVE SOLUBLE TNFRI, TNFR2 AND IL2 IN PATIENTS Russian patent published in 2010 - IPC A61K39/395 A61K38/19 A61P35/00 A61M1/38 

FIELD: medicine.

SUBSTANCE: invention concerns medicine, namely oncology, and aims at inducing the immune response in patients with higher levels of soluble receptors of tumour necrosis factor (sTNFRl, sTNFR2) and soluble receptors of interleukine-2 (sIL2R). Therefor, the patient's blood purpose circulates through a filter or a column wherein contacts to effective amount of binding partners. Said binding partners represent immobilised TNFRI, TNFR2 and IL2 or immobilised antibodies binding with sTNFRl, sTNFR2 and sIL2. The blood or plasma levels of receptors are reduced until they become below the normal. It involves at least 12 procedures. The amount of treated plasma per one procedure is approximately equal to one volume of extracellular fluid.

EFFECT: invention allows for selective removal of soluble cytokine receptors with inducing the immune response and ensuring remission of the diseases characterised by high production of sTNFRl, sTNFR2 and sIL2 including malignant tumours.

10 cl, 4 tbl, 1 ex, 5 dwg