METHOD FOR PREDICTION OF VARIABILITY OF PEMPHIGUS CLINICAL FORM Russian patent published in 2010 - IPC A61B10/00 G01N33/53 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to laboratory analysis and can be used in dermatology. The method aims at higher accuracy of prediction ensured by more reliable profiling of target antigens of autoimmune pemphigus. That is ensured by analysing a clinically intact skin area by the direct immunofluorescence. Fixed immunoglobulin G is localised. When localising IgG in an intercellular substance of all epidermic layers, potential pemphigus deformation is predicted; IgG observed not in all layers shows low probability of variability of pemphigus clinical form. The offered method allows for prediction of potential transition between clinical forms.

EFFECT: it ensures more effective specification of therapeutic approach and management of the patient.

3 dwg, 4 ex