RASAGILINE COMPOSITIONS DEGRADING IN MOUTH CAVITY Russian patent published in 2010 - IPC A61K31/135 A61K47/26 A61K9/22 A61K9/52 A61P25/16 

Abstract RU 2389482 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: solid pharmaceutical composition contains rasagiline or a pharmaceutically acceptable salt of rasagiline and particles of afibrillar microstructure of at least two sugar alcohols. The solid pharmaceutical composition containing rasagiline or its pharmaceutically acceptable salt can contain mixed aerating agent improving fluidity, and the particles of afibrillar microstructure of at least two sugar alcohols, additional sugar alcohol, additional fluidity improving agent and additional aerating agent. This invention presents the method of treating an individual suffering from Parkinson's disease.

EFFECT: rasagiline tablets under the invention are characterised by low fragility, sufficient hardness and quickly degrade in mouth cavity, eg for 50-90 seconds.

58 cl, 2 tbl, 7 ex

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RU 2 389 482 C2

Authors

Patashnik Shulamit

Lajt Dehniella

Gilbert Adrian

Dates

2010-05-20Published

2005-11-17Filed