FIELD: chemistry, biology.
SUBSTANCE: synthetic genes which code modified proteins E1 and E12 of the red rot virus provided. In order to produce these proteins in plants, synthetic genes are incorporated into the viral vector based on the potato virus X genome. Plants are infected with agrobacteria containing the obtained recombinant viral vector. Reproduction of the viral vector and synthesis of the product on a high level take place in the plants.
EFFECT: production of E1 and E12 using designed viral expression systems in Nicotiana benthamiana plants can be used to make a potential recombinant vaccine for red rot.
14 cl, 4 dwg, 4 ex
Title | Year | Author | Number |
---|---|---|---|
RECOMBINANT VIRAL VECTOR AND EXPRESSION SYSTEM IN PLANT CELLS OF HYBRID PROTEIN CONTAINING EXTRACELLULAR DOMAIN OF PROTEIN M2 OF INFLUENZA VIRUS ATTACHED TO CORE ANTIGEN OF HEPATITIS B VIRUS | 2010 |
|
RU2460796C2 |
VIRUS VECTOR FOR PRODUCTION OF RECOMBINANT PROTEINS IN PLANTS | 2008 |
|
RU2402607C2 |
METHOD OF OBTAINING THE ANTIBODY, WHICH SPECIFICALLY BINDS THE DOMAIN OF THE HER2/NEU EXCELLULAR PART OF THE HER2/NEU ONCOPROTEIN, IN THE PLANT, THE ANTIBODY, WHICH IS OBTAINED BY MEANS OF THIS METHOD AND ITS APPLICATION | 2016 |
|
RU2648161C2 |
ANTIBODY AGAINST VESSEL ENDOTHELIUM GROWTH FACTOR AND METHOD OF ANTIBODY PRODUCTION IN PLANT | 2009 |
|
RU2412251C1 |
RUBELLA VACCINE ON THE BASIS OF A STRUCTURALLY-MODIFIED VIRUS OF PLANTS AND A METHOD FOR ITS PRODUCTION | 2016 |
|
RU2660563C2 |
METHOD OF HER2/neu ONCOGENE ANTIBODY SUPERPRODUCTION IN PLANT | 2007 |
|
RU2370280C2 |
PROTEIN EXPRESSION SYSTEMS | 2009 |
|
RU2539793C2 |
RECOMBINANT PLASMID DNA pBi101-IL18 ENCODING HUMAN INTERLEUKIN-18 SYNTHESIS IN TRANSGENIC PLANTS | 2005 |
|
RU2302460C1 |
ANTIGEN FOR RECOMBINANT VACCINE AGAINST RUBELLA VIRUS | 2019 |
|
RU2709328C1 |
PROTEIN EXPRESSION IN PLANTS | 2012 |
|
RU2711936C2 |
Authors
Dates
2010-05-27—Published
2008-10-21—Filed