FIELD: medicine.
SUBSTANCE: purified RNA synthesised in vitro by nonviral transfection is introduced into placental and cord cells. RNA comprises at least one sequence providing cell transition to a pluripotent state.
EFFECT: method allows increasing efficiency of preparing selected somatic pluripotent cells, reducing probability of oncogenesis and other negative consequences of cell reprogramming, and eliminating invasiveness at the stage of preparation of the cell material.
10 dwg, 3 ex
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Authors
Dates
2010-09-20—Published
2009-04-10—Filed