FIELD: medicine.
SUBSTANCE: method for biological modelling of staphylococcal allergy involves the sensitisation of cavies with staphylococci suspension 5.0-10.0 bln/ml deactivated by autoclaving and detoxicated in 0.2% formalin, and sorbed on aluminium hydroxide 3-5 mg/ml. The suspension prepared as described above is single subcutaneously introduced to cavies in the amount 0.5-1.0 ml per one animal. The allergic reaction is provoked by the intracutaneous introduction of 0.1 ml of staphylococcal allergen dissolved 1:10, 1:20 and 1:40. The reaction is estimated by skin hyperemia 24 hours later.
EFFECT: permanent allergy simulation in laboratory animals.
4 ex
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