FIELD: chemistry.
SUBSTANCE: method of producing nanoparticles of low-molecular chitosan involves preparing a solution of pre-purified low-molecular chitosan in filtered 1-2 wt % aqueous acetic acid, adding solutions of hydroxides of alkali metals or ammonia for 2 hours, dispersing the system using a mechanical mixer at a rate of 200-300 rpm at temperature 20°C to pH 6.9-7.0. Further, the dispersion is centrifuged at 10000 rpm. The obtained solid residue is redispersed in bidistillate while mechanically mixing at a rate of 200-300 rpm at temperature 20°C.
EFFECT: invention simplifies the method of producing nanoparticles of low-molecular chitosan and apparatus design without formation of undesirable harmful substances.
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Authors
Dates
2011-09-10—Published
2010-03-30—Filed