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2 435 777

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(51)

IPC

C07D498/12(2006-01-01)

(21) (22)

Application

2010117938/04, 2010-05-04

(24)

Start date

2010-05-04

(22)

Actual filing date

2010-05-04

(45)

Published

2011-12-10

(72)

Inventor

Maslivets Andrej NikolaevichStepanova Ekaterina Evgen'EvnaMakhmudov Ramiz Ragibovich

(73)

Holder

Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Universitet"

16-ALKOXY-14-ARYL-3,15-DIOXA-10-AZATETRACYCLO [8,7,0,0.0] HEPTADECA-4,6,8,13-TETRAENE-2,11,12-TRIONES AND SYNTHESIS METHODS THEREOF Russian patent published in 2011 - IPC C07D498/12

Abstract RU 2435777 C1

FIELD: chemistry.

SUBSTANCE: present invention relates to novel 16-alkoxy-14-aryl-3,15-dioxa-10-azatetracyclo[8.7.0.0^1,13.0^4,9]heptadeca-4,6,8,13-tetraene-2,11,12-triones , where Alk = Et (a-c), Bu (d), Ar = Ph (a, d), C₆H₄Br-4(b), C₆H₄OMe-4(c). Such compounds are found to exhibit analgesic activity.

EFFECT: invention relates to methods of producing described compounds through reaction of aroylpyrrolo[2,1-c][1,4]benzoxazine-1,2,4(4H)-triones with alkyl vinyl esters while boiling in the medium of an inert aprotic solvent.

3 cl, 5 ex, 1 tbl

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RU 2 435 777 C1

Authors

Maslivets Andrej Nikolaevich

Stepanova Ekaterina Evgen'Evna

Makhmudov Ramiz Ragibovich

Dates

2011-12-10—Published

2010-05-04—Filed