3-AROYL-2-HYDROXY-2-(2-OXOCYCLOALKYL)PYRROLO[2,1-C][1,4]BENZOXAZINE-1,4(2H)-DIONES HAVING ANALGESIC ACTIVITY AND METHODS FOR PRODUCTION THEREOF Russian patent published in 2015 - IPC C07D498/04 A61K31/5383 A61P29/00 

Abstract RU 2564440 C1

FIELD: chemistry.

SUBSTANCE: invention relates to 3-aroyl-2-hydroxy-2-(2-oxocycloalkyl)pyrrolo[2,1-c][1,4]benzoxazine-1,4(2H)-diones of formula (I) , having analgesic activity and a method for production thereof. In general formula (I) Ar = Ph (a-c), C6H4Br-4 (d), C6H4OMe-4 (e), n = 1 (a), 2 (b, d, e), 3 (c).

EFFECT: higher activity of the compounds.

3 cl, 1 tbl, 6 ex

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RU 2 564 440 C1

Authors

Maslivets Andrej Nikolaevich

Stepanova Ekaterina Evgen'Evna

Makhmudov Ramiz Ragibovich

Dates

2015-10-10Published

2014-06-03Filed