FIELD: chemistry.
SUBSTANCE: present invention relates to novel synthesis of 11H-indolo[2,3-c]quinoline derivatives of formula I, which can be used in synthesis of novel preparations for pharmaceutical purposes. In the method of producing 11H-indolo[2,3-c]quinoline derivatives of general formula I
, the corresponding 4-[2-(2-nitrophenyl)-1H-indol-3-yl]-but-3-en-2-ones II are boiled in acetic acid in the presence of twenty-fold molar excess of carbonyl iron for 5 minutes.
EFFECT: method widens the range of obtained products and simplifies the process owing to use of other initial compounds and conditions.
1 cl, 4 ex, 2 tbl
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Authors
Dates
2012-01-10—Published
2010-07-05—Filed