METHOD OF PREDICTING ISCHEMIC HEART DISEASE COURSE Russian patent published in 2012 - IPC G01N33/68 

FIELD: medicine.

SUBSTANCE: invention describes method of predicting course of ischemic heart disease by analysis of blood serum, with simultaneous determination before and after treatment of HDLP, total cholesterol and LP (a), by additional processing of 0.3 ml of 0.1% Triton X-100 solution and incubation for 15 min at 20°C, mixing mixture by shaking 120 times per 1 min, with further incubation of patient's blood serum with Sudan B solution for 1 hour in dark thermostat at 40°C, and after that introduction into a hollow in agarose gel with base area 4x20 mm for electrophoresis and further fixation of electrophoregrams, their drying, densitometry and with simultaneous reduction of total cholesterol by 20% and more and LP (a) by 35% and more and increase of HDLP from 13% to 28% and more in comparison with initial level prognosis of disease treatment is considered favourable, contributing to passing of stenocardia of tension from functional class III-IV in functional class I-II, and if total cholesterol decreases by less than 20%, LP (a) level less than 35% and increase of HDLP to 27% in comparison with initial level, prediction is considered to be unfavourable.

EFFECT: increase of sensitivity and accuracy of prediction of ischemic heart disease course.

2 ex, 6 dwg