SET OF FRANCISELLA TULARENSIS BACTERIA STRAINS FOR PRODUCTION OF REFERENCE DNA PREPARATION SET, SET OF DNA PREPARATIONS FOR GENETICALLY DIAGNOSTIC RESEARCH Russian patent published in 2012 - IPC C12N1/00 C12Q1/68 C12N15/31 C12R1/00 

FIELD: agriculture.

SUBSTANCE: invention represents reference strains Francisella tularensis of tularensis subtype, including two genetic groups AI and AII, of holartica subtype, including biovars japonica, erythromycin-sensitive and erythromycin-resistant, Ery^s and Ery^R, and of mediasiatica subtype. Strains are deposited in the State Collection of Pathogenic Microbes "Microbe". All strains are natural, apart from the strain of holartica subtype, biovar japonica, which is extracted from a human being. Strains are produced by selection of clones that stably preserve phenotypic properties and containing genes, nucleotide sequence of which is specified for the type and subtype. The set of reference DNA preparations is created on the basis of these strains and may be used for genetic and immunological research.

EFFECT: using the invention will make it possible to increase efficiency of diagnostic research, to standardise and to increase quality of diagnostic preparations at production stages.

4 cl, 4 dwg, 1 tbl, 10 ex