METHOD OF PRODUCING 1,3-DI(R-THIO)ADAMANTANES Russian patent published in 2012 - IPC C07C319/18 C07C321/28 C07D277/70 

Abstract RU 2448956 C1

FIELD: chemistry.

SUBSTANCE: invention relates to the chemistry of adamantane derivatives, specifically to a method of producing 1,3-di(R-thio)adamantanes of general formula: , where (1); (2); (3); (4). The method involves binding disulphides to 1,3-dehydroadamantane, said disulphides being selected from: diphenyl disulphide, n,n'-bis-(4-bromophenyl)disulphide, 2,2'-dibenzthiazolyl disulphide, n,n'-bis-(4-aminophenyl)disulphide with molar ratio of reactants equal to 1:1.1, in the medium of an inert solvent, e.g., diethyl ether, tetrahydrofuran or methylene chloride, in the presence of catalytic amounts of sodium hydroxide at temperature 35-65°C for 2-3 hours.

EFFECT: novel single-step method of producing 1,3-di(R-thio)adamantanes, which enables to obtain disclosed compounds with high output.

1 cl, 4 ex

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RU 2 448 956 C1

Authors

Butov Gennadij Mikhajlovich

Mokhov Vladimir Mikhajlovich

Tsapkova Julija Vladimirovna

Ivankina Ol'Ga Mikhajlovna

Zyk Nikolaj Vasil'Evich

Antipin Roman L'Vovich

Gavrilova Anna Jur'Evna

Dates

2012-04-27Published

2011-02-01Filed