DIAGNOSTIC TECHNIQUE FOR BREAST CANCER BY BLOOD PLASMA INTERLEUKIN IL-8 AND/OR IL-18 RNA LEVEL Russian patent published in 2012 - IPC G01N33/50 C12Q1/68 

Abstract RU 2451937 C2

FIELD: medicine.

SUBSTANCE: technique is based on measuring a blood plasma interleukin IL-8 and/or IL-18 RNA level and comparing an IL-8 and/or IL-18 RNA presentation level and a reference transcript presentation level. The technique is implemented by using reverse transcription and a real-time polymerase chain reaction. The ABL and/or HPRT and/or IL lb RNA are used as reference transcripts. The result is considered to be positive if observing a ten times difference of the IL-8 and HPRT RNA presentation levels.

EFFECT: using the declared technique enables early diagnosis of breast cancer.

1 ex, 1 dwg

Similar patents RU2451937C2

Title Year Author Number
METHOD FOR DIAGNOSING BREAST CANCER BY LEVEL OF EXPRESSION OF IL-10 AND/OR IL-17 MRNA IN BLOOD PLASMA 2020
  • Lolomadze Elena Anatolevna
  • Kometova Vlada Vladimirovna
  • Rodionov Valerij Vitalevich
  • Rebrikov Denis Vladimirovich
RU2752971C1
METHOD FOR DIAGNOSING BREAST CANCER BY LEVEL OF MRNA TGEβ AND TNFα IN BLOOD PLASMA 2019
  • Lolomadze Elena Anatolevna
  • Kometova Vlada Vladimirovna
  • Rodionov Valerij Vitalevich
  • Rebrikov Denis Vladimirovich
RU2742209C1
METHOD FOR DIAGNOSING BREAST CANCER AND OVARIAN CANCER BY MMP-9 MRNA LEVEL IN BLOOD PLASMA 2020
  • Lolomadze Elena Anatolevna
  • Kometova Vlada Vladimirovna
  • Rodionov Valerij Vitalevich
  • Rebrikov Denis Vladimirovich
RU2745424C1
METHOD FOR EVALUATING PYORRHOEA ON PARADONTIUM BASED ON LEVEL OF HUMAN INTERLEUKIN-8 (IL-8) GENE MRNA 2015
  • Zorina Oksana Aleksandrovna
  • Ajmadinova Nelli Kamilevna
  • Shibaeva Anna Valerevna
  • Rebrikov Denis Vladimirovich
  • Trubnikova Elena Vladimirovna
  • Shevelev Aleksej Borisovich
  • Kudykina Yuliya Konstantinovna
  • Boldinova Elizaveta Olegovna
  • Petrukhina Natalya Borisovna
  • Trofimov Dmitrij Yurevich
RU2607041C2
DIAGNOSTIC TECHNIQUE FOR BREAST CANCER AND OVARIAN CANCER 2017
  • Ivanov Yurij Dmitrievich
  • Pleshakova Tatyana Olegovna
  • Malsagova Kristina Akhmedovna
  • Kozlov Andrej Fedorovich
  • Archakov Aleksandr Ivanovich
  • Popov Vladimir Pavlovich
RU2696114C2
METHOD OF PREDICTING THE DEVELOPMENT OF METASTASES IN PATIENTS WITH UNRESECTABLE TRIPLE-NEGATIVE BREAST CANCER 2023
  • Molchanov Oleg Evgenevich
  • Maistrenko Dmitrii Nikolaevich
  • Granov Dmitrii Anatolevich
  • Semenov Konstantin Nikolaevich
  • Sharoiko Vladimir Vladimirovich
  • Popova Alena Aleksandrovna
RU2802141C1
METHOD FOR PREDICTING THE DURATION OF A RELAPSE-FREE PERIOD IN PATIENTS WITH RESECTABLE THRICE-NEGATIVE BREAST CANCER 2021
  • Molchanov Oleg Evgenevich
  • Maistrenko Dmitrii Nikolaevich
  • Granov Dmitrii Anatolevich
  • Popova Alena Aleksandrovna
  • Semenov Konstantin Nikolaevich
  • Sharoiko Vladimir Vladimirovich
RU2780922C1
DIAGNOSTIC TECHNIQUE FOR VAGINITIS IN PREGNANT WOMEN BY INTERLEUKINE GENE IRNA EXPRESSION IN VAGINAL SMEARS 2011
  • Burmenskaja Ol'Ga Vladimirovna
  • Medzhidova Marzhana Kapurovna
  • Nepsha Oksana Sergeevna
  • Donnikov Andrej Evgen'Evich
  • Trofimov Dmitrij Jur'Evich
  • Sukhikh Gennadij Tikhonovich
RU2510855C2
METHOD OF PRODUCING ANTIGEN-SPECIFIC CYTOTOXIC CELLS HAVING ACTIVITY AGAINST BREAST CANCER CELLS 2013
  • Sennikov Sergej Vitalevich
  • Shevchenko Yuliya Aleksandrovna
  • Khantakova Yuliya Nikolaevna
  • Kurilin Vasilij Vasilevich
  • Lopatnikova Yuliya Anatolevna
  • Sidorov Sergej Vasilevich
  • Zajtsev Sergej Alekseevich
  • Maksyutov Amir Zakievich
  • Gavrilova Elena Vasilevna
  • Maksyutov Rinat Amirovich
RU2596920C2
METHOD FOR DETERMINING THERAPEUTIC APPROACH IN PATIENTS WITH METASTATIC FORMS AND RECURRENT TRIPLE-NEGATIVE BREAST CANCER 2023
  • Molchanov Oleg Evgenevich
  • Maistrenko Dmitrii Nikolaevich
  • Popova Alena Aleksandrovna
  • Semenov Konstantin Nikolaevich
  • Popova Elena Aleksandrovna
  • Protas Aleksandra Vladimirovna
  • Mikolaichuk Olga Vladislavovna
  • Sharoiko Vladimir Vladimirovich
  • Granov Dmitrii Anatolevich
RU2818730C1

RU 2 451 937 C2

Authors

Rebrikov Denis Vladimirovich

Dates

2012-05-27Published

2010-06-07Filed