METHOD OF PREDICTING RELAPSE-FREE SURVIVAL BY CLINICAL AND PATHOLOGIVCAL FACTORS IN PATIENTS WITH METASTASES OF COLORECTAL CANCER IN LIVER AND AFTER ITS RESECTION Russian patent published in 2012 - IPC A61B5/107 G01N1/28 

Abstract RU 2452373 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to surgery and oncology. In order to predict relapse-free survival after liver resection in patients with metastases of colorectal cancer on the basis of combination of maximal size and quantity of metastases by the table "Clinical and pathological factors", included into the description, level of factor importance is determined and the number of points corresponding to the value of clinical-pathological factor is found. Obtained points are summed up, after which prognosis of relapse-free survival P(K) is determined by formula: where: K (Fi; d; m) is the function of Fi factor importance with specified values of d and m, where d is the maximal size of MTS, m is the number of MTS; n is the number of used factors, i is the index of summation. If P(K) equals 100-60 points, prognosis of relapse-free survival is bad, risk of relapse development is predicted within 12 months. In case of 59-30 points - prognosis is moderate, risk of relapse development - within 12-23.9 months. In case of 29-10 points prognosis is good, there is no risk of relapse development or it is predicted after 24 months.

EFFECT: method makes it possible to predict relapse of the disease after liver resection caused by metastatic colorectal cancer.

2 ex, 2 tbl

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RU 2 452 373 C1

Authors

Chzhao Aleksej Vladimirovich

Kovalenko Jurij Alekseevich

Chugunov Andrej Olegovich

Galankina Irina Evgen'Evna

Kozlov Maksim Viktorovich

Dates

2012-06-10Published

2011-01-14Filed