5-[1'-(DECAHYDRO-7-HYDROXY-1,1,3a,7-TETRAMETHYL-1H-CYCLOPROPA[A]NAPHTHALEN-4-YL)-3'-METHYLBUTYL]-2,4,6-TRIHYDROXY-1,3-BENZENE DICARBOXALDEHYDE AS MEDICINAL AGENTS Russian patent published in 2012 - IPC C07C47/57 A61K31/11 A61K36/61 A61P25/28 

Abstract RU 2453527 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a pharmaceutical composition containing primary material in form of at least one compound selected from 5-[(1'R)-1'-[(1aS,3aS,4S,7R,7aR,7bS)-decahydro-7-hydroxy-1,1,3a,7-tetramethyl-1H-cyclopropa[A]naphthalen-4-yl]-3'-methylbutyl]-2,4,6-trihydroxy-1,3-benzene dicarboxaldehyde and 5-[(1'S)-1'-[(1aS,3aS,4S,7R,7aR,7bS)-decahydro-7-hydroxy-1,1,3a,7-tetramethyl-1H-cyclopropa[A]naphthalen-4-yl]-3'-methylbutyl]-2,4,6-trihydroxy-1,3-benzene dicarboxaldehyde, in a combination with an acceptable carrier, for treating and/or preventing disorders or pathologies which are a result of a disorder of reuptake of the following neuromediators: dopamine, serotonin and/or noradrenaline, as well as to use of at least one compound selected from 5-[(1'R)-1'-[(1aS,3aS,4S,7R,7aR,7bS)-decahydro-7-hydroxy-1,1,3a,7-tetramethyl-1H-cyclopropa[A]naphthalen-4-yl]-3'-methylbutyl]-2,4,6-trihydroxy-1,3-benzene dicarboxaldehyde and 5-[(1'S)-1'-[(1aS,3aS,4S,7R,7aR,7bS)-decahydro-7-hydroxy-1,1,3a,7-tetramethyl-1H-cyclopropa[A]naphthalen-4-yl]-3'-methylbutyl]-2,4,6-trihydroxy-1,3-benzene dicarboxaldehyde to obtain a medicinal agent.

EFFECT: improved method.

9 cl, 2 ex, 1 tbl

Similar patents RU2453527C2

Title Year Author Number
NEW EUCALYPTUS EXTRACT, METHOD FOR PRODUCING AND USING IT FOR THERAPEUTIC PURPOSES 2007
  • Fiorini-Pjujbare Kristel'
  • Fabr Bernar
  • Shovehn Sesil'
  • Zhulia Filipp
RU2445112C2
CONDENSED TROPANIC DERIVATIVES AS NEUROMEDIATOR REVERSE CAPTURE INHIBITORS 1996
  • Sheel'-Krjuger Jorgen
  • Ol'Sen Gunar M.
  • Nil'Sen Ehl'Sebet Ehstergor
  • Dakhl' B'Jarne Khugo
  • Ensen Lejf Khel'T
RU2162469C2
LIGUSTILIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS 2007
  • De Sez'E Antuan
  • Goral'Chik Regina
  • Shuler Gede
RU2462462C2
DERIVATIVES OF 8-AZABICYCLO[3,2,1]OCT-2-ENE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF DRUG PREPARING, METHODS OF INHIBITION OF REUPTAKE OF MONOAMINE NEUROMEDIATING AGENT, ESPECIALLY, SEROTONIN 1996
  • Mol'Dt Peter
  • Sheel'-Krjuger Jorgen
  • Ol'Sen Gunnar M.
  • Nil'Sen Ehl'Sebet Ehstergord
RU2157372C2
3-PHENOXYMETHYL-PYRROLIDINE COMPOUNDS 2010
  • Stehndzhlehnd Ehrik L.
  • Saito Dajsuke Roland
  • Kh'Juz Adam
  • Shmidt Dzhehjn
  • Van Dajk Pristsilla
  • Patterson Lori Dzhin
RU2535669C2
NOVEL CHROMAN-2-ONE DERIVATIVES AND USE THEREOF AS MONOAMINE NEUROMEDIATOR REUPTAKE INHIBITORS 2005
  • Peters Dan
  • Ol'Sen Gunnar M.
  • Sheel'-Krjuger Jorgen
  • Niel'Sen Ehl'Sebet Ehstergord
RU2382040C2
SHIP1 MODULATORS AND METHODS RELATED THERETO 2014
  • Makkenzi Llojd F.
  • Makruri Tomas B.
  • Kharvig Kertis
  • Bogutski Devid
  • Rejmond Dzheffri R.
  • Pettigryu Dzheremi D.
RU2679805C2
SELECTIVE GLYCOSIDASE INHIBITORS AND USE THEREOF 2011
  • Kaul Ramesh
  • Makichern Ernest Dzh.
  • Mu Chanvej
  • Selnik Garold G.
  • Vokadlo Devid Dzh.
  • Van Yaode
  • Vej Chzhunyun
  • Chzhou Yuansi
  • Chzhu Yunbao
RU2609210C2
2,3-TRANS-DISUBSTITUTED TROPAN DERIVATIVE, METHOD OF ITS SYNTHESIS, PHARMACEUTICAL COMPOSITION 1997
  • Shel'-Krjuger Jergen
  • Mol'T Peter
  • Vot'En Frank
RU2167876C2
DERIVATIVES OF TETRAHYDROISOQUINOLINE, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF, METHOD FOR INHIBITION OF SYNAPTIC UPTAKE OF DOPAMINE AND TREATMENT METHOD 2000
  • Bek Dzhejms P.
  • Smit Mark A.
RU2293728C2

RU 2 453 527 C2

Authors

Fiorini-Pjujbare Kristel'

Zhulia Filipp

Dates

2012-06-20Published

2009-01-13Filed