METHOD FOR PLACENTAL MICROCIRCULATION DISORDER CORRECTION WITH POLYVITAMIN-MINERAL COMPLEX IN ADMA-LIKE GESTOSIS MODELS IN EXPERIMENT Russian patent published in 2012 - IPC G09B23/28 A61K31/51 A61K31/593 A61K33/26 A61P15/06 

Abstract RU 2457548 C1

FIELD: medicine.

SUBSTANCE: ADMA-like gestosis model is experimentally reproduced in laboratory pregnant rats by introducing NO-synthase inhibitor L-NAME. It is combined with the pathology correction by the 7-day daily intragastric introduction of the vitamin-mineral preparation 'Complivit Trimestrum Trimester 3' 0.084 tab/kg/day.

EFFECT: method provides the manifested correction of placental microcirculation disorder ensured by endothelial protective effect of the preparation in the proper dosages.

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Authors

Pokrovskij Mikhail Vladimirovich

Gureev Vladimir Vladimirovich

Poljanskaja Oksana Sergeevna

Artjushkova Elena Borisovna

Korokin Mikhail Viktorovich

Gudyrev Oleg Sergeevich

Belous Aleksandr Sergeevich

Tsybul'Skij Igor' Valer'Evich

Kotel'Nikova Lilija Viktorovna

Denisjuk Tat'Jana Alekseevna

Terekhova Elena Gennad'Evna

Babko Anna Vladimirovna

Alekhin Sergej Aleksandrovich

Alekhina Valerija Valer'Evna

Mostovoj Aleksandr Sergeevich

Lebedev Kirill Aleksandrovich

Starosel'Tseva Ol'Ga Aleksandrovna

Zhukov Sergej Vladimirovich

Kaplin Anton Nikolaevich

Dates

2012-07-27Published

2011-06-01Filed