Show metadata Hide metadata

(19)

(11)

2 462 253

(13)

(51)

IPC

A61K31/7048(2006-01-01)

A61P31/04(2006-01-01)

(21) (22)

Application

2011136308/15, 2011-08-31

(24)

Start date

2011-08-31

(22)

Actual filing date

2011-08-31

(45)

Published

2012-09-27

(72)

Inventor

Pokrovskij Mikhail VladimirovichGureev Vladimir VladimirovichPoljanskaja Oksana SergeevnaArtjushkova Elena BorisovnaKorokin Mikhail ViktorovichGudyrev Oleg SergeevichBratchikov Oleg IvanovichChernomortseva Elena StanislavovnaFilimonov Vjacheslav AleksandrovichBelous Aleksandr SergeevichTsybul'Skij Igor' Valer'EvichKotel'Nikova Lilija ViktorovnaTerekhova Elena Gennad'EvnaBabko Anna VladimirovnaAlekhin Sergej AleksandrovichAlekhina Valerija Valer'EvnaMostovoj Aleksandr SergeevichZhernakov Evgenij VladislavovichGolovchenko Il'Ja OlegovichKhadieva Taisija AbduladirovnaPakhomov Sergej Petrovich

(73)

Holder

Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhranenija I Sotsial'Nogo Razvitija Rossijskoj Federatsii

METHOD FOR EXPERIMENTAL AZYTHROMYCIN CORRECTION OF PLACENTAL MICROCIRCULATION DISORDER IN ADMA-LIKE GESTOSIS MODELS Russian patent published in 2012 - IPC A61K31/7048 A61P31/04

Abstract RU 2462253 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine. A method involves a reproducible ADMA-like gestosis model in pregnant female rats Wistar by the daily 7-day intraperitoneal introduction of L-nitro-arginine-methyl ester 25 mg/kg. This daily 7-day intraperitoneal introduction is combined with the intragastric introduction of the antibacterial preparation Azythromycin 30 mg/kg/day of the group of macrolides.

EFFECT: method is effective for correction of placental microcirculation disorder.

1 ex

Similar patents RU2462253C1

Title	Year	Author	Number
METHOD FOR PLACENTAL MICROCIRCULATION DISORDER CORRECTION WITH POLYVITAMIN-MINERAL COMPLEX IN ADMA-LIKE GESTOSIS MODELS IN EXPERIMENT	2011	Pokrovskij Mikhail Vladimirovich Gureev Vladimir Vladimirovich Poljanskaja Oksana Sergeevna Artjushkova Elena Borisovna Korokin Mikhail Viktorovich Gudyrev Oleg Sergeevich Belous Aleksandr Sergeevich Tsybul'Skij Igor' Valer'Evich Kotel'Nikova Lilija Viktorovna Denisjuk Tat'Jana Alekseevna Terekhova Elena Gennad'Evna Babko Anna Vladimirovna Alekhin Sergej Aleksandrovich Alekhina Valerija Valer'Evna Mostovoj Aleksandr Sergeevich Lebedev Kirill Aleksandrovich Starosel'Tseva Ol'Ga Aleksandrovna Zhukov Sergej Vladimirovich Kaplin Anton Nikolaevich	RU2457548C1
METHOD FOR ENDOTHELIAL DYSFUNCTION CORRECTION WITH POLYVITAMIN-MINERAL COMPLEX IN ADMA-LIKE GESTOSIS MODELS IN EXPERIMENT	2011	Pokrovskij Mikhail Vladimirovich Gureev Vladimir Vladimirovich Poljanskaja Oksana Sergeevna Artjushkova Elena Borisovna Korokin Mikhail Viktorovich Gudyrev Oleg Sergeevich Belous Aleksandr Sergeevich Tsybul'Skij Igor' Valer'Evich Kotel'Nikova Lilija Viktorovna Denisjuk Tat'Jana Alekseevna Terekhova Elena Gennad'Evna Babko Anna Vladimirovna Alekhin Sergej Aleksandrovich Alekhina Valerija Valer'Evna Mostovoj Aleksandr Sergeevich Lebedev Kirill Aleksandrovich Starosel'Tseva Ol'Ga Aleksandrovna Zhukov Sergej Vladimirovich Kaplin Anton Nikolaevich	RU2460149C1
METHOD FOR ENDOTHELIAL DYSFUNCTION CORRECTION WITH AZITHROMYCIN IN ADMA-LIKE GESTOSIS MODEL IN EXPERIMENT	2012	Pokrovskij Mikhail Vladimirovich Pokrovskaja Tat'Jana Grigor'Evna Kochkarov Vladimir Iskhakovich Korokin Mikhail Viktorovich Gudyrev Oleg Sergeevich Arustamova Anna Aleksandrovna Zhernakov Evgenij Vladislavovich Golovchenko Igor' Olegovich Gureev Vladimir Vladimirovich Poljanskaja Oksana Sergeevna Tsybul'Skij Igor' Valer'Evich Mostovoj Aleksandr Sergeevich	RU2507595C2
METHOD FOR PLACENTAL MICROCIRCULATION CORRECTION BY RECOMBINANT ERYTHROPOIETIN IN ADMA-LIKE GESTOSIS MODEL	2011	Pokrovskij Mikhail Vladimirovich Gureev Vladimir Vladimirovich Poljanskaja Oksana Sergeevna Mal'Tseva Natal'Ja Viktorovna Korokina Lilija Viktorovna Pokrovskaja Tat'Jana Grigor'Evna Gureeva Elena Gennad'Evna Kochkarov Vladimir Iskhakovich Bondarenko Evgenija Valer'Evna Danilenko Ljudmila Mikhajlovna Zhernakov Evgenij Vladislavovich Golovchenko Il'Ja Olegovich Khadieva Taisija Abduladirovna Pakhomov Sergej Petrovich Denisjuk Tat'Jana Alekseevna Kotel'Nikova Lilija Viktorovna Alekhin Sergej Aleksandrovich Alekhina Valerija Valer'Evna Korokin Mikhail Viktorovich Gudyrev Oleg Sergeevich Belous Aleksandr Sergeevich Tsybul'Skij Igor' Valer'Evich	RU2466462C1
METHOD FOR PLACENTAL MICROCIRCULATION DISORDER CORRECTION IN ADMA-LIKE GESTOSIS MODELS IN EXPERIMENT	2010	Pokrovskij Mikhail Vladimirovich Gureev Vladimir Vladimirovich Barsuk Anna Aleksandrovna Proskurjakova Elena Vital'Evna Lazareva Galina Anatol'Evna Pokrovskaja Tat'Jana Grigor'Evna Poljanskaja Oksana Sergeevna Gureeva Elena Gennadievna Korokin Mikhail Viktorovich Gudyrev Oleg Sergeevich Belous Aleksandr Sergeevich Tsybul'Skij Igor' Valer'Evich Danilenko Ljudmila Mikhajlovna Kochkarov Vladimir Iskhakovich Novikov Oleg Olegovich	RU2432618C1
METHOD FOR PLACENTAL MICROCIRCULATION DISORDER CORRECTION IN ADMA-LIKE GESTOSIS MODEL	2010	Pokrovskij Mikhail Vladimirovich Gureev Vladimir Vladimirovich Pokrovskaja Tat'Jana Grigor'Evna Poljanskaja Oksana Sergeevna Gureeva Elena Gennadievna Korokin Mikhail Viktorovich Gudyrev Oleg Sergeevich Belous Aleksandr Sergeevich Tsybul'Skij Igor' Valer'Evich Danilenko Ljudmila Mikhajlovna Novikov Oleg Olegovich Tsepeleva Svetlana Aleksandrovna Kotel'Nikova Lilija Viktorovna Denisjuk Tat'Jana Alekseevna Losenok Polina Igorevna Stupakova Elena Gennad'Evna	RU2453000C1
METHOD FOR CORRECTION OF ENDOTHELIAL DYSFUNCTION OF PHARMACOLOGICAL PRE-CONDITIONING BY NICORANDIL IN SIMULATED ADMA-LIKE GESTOSIS EXPERIMENTALLY	2014	Gureev Vladimir Vladimirovich Pokrovskij Mikhail Vladimirovich Molchanova Ol'Ga Viktorovna Kochkarov Vladimir Iskhakovich Pokrovskaja Tat'Jana Grigor'Evna Peresypkina Anna Aleksandrovna Korokin Mikhail Viktorovich Gudyrev Oleg Sergeevich Shabel'Nikova Anna Sergeevna Jakushev Vladimir Ivanovich Korokina Lilija Viktorovna Lazareva Galina Anatol'Evna Stupakova Elena Gennad'Evna Gureeva Elena Gennadievna	RU2543359C1
METHOD OF CORRECTION OF PLACENTAL MICROCIRCULATION DISORDERS WITH 2-HYDROXYPHENYLTHIOACETAMIDE DERIVATIVES	2019	Gureev Vladimir Vladimirovich Pokrovskij Mikhail Vladimirovich Lokteva Tatyana Ivanovna Antsiferova Oksana Evgenevna Yurakova Alesya Viktorovna Pokrovskaya Tatyana Grigorevna Peresypkina Anna Aleksandrovna Korokin Mikhail Viktorovich Gudyrev Oleg Sergeevich Pobeda Anna Sergeevna Yakushev Vladimir Ivanovich Korokina Liliya Viktorovna Lazareva Galina Anatolevna Gureeva Elena Gennadievna Zhilinkova Lyudmila Anatolevna Zatolokina Mariya Alekseevna Shchurovskaya Kristina Vladimirovna Kolesnichenko Pavel Dmitrievich Pakhomov Sergej Petrovich Severinova Olga Vladimirovna Golubev Ivan Vladimirovich Ivakhno Elena Nikolaevna Povetka Elena Evgenevna Gureeva Anastasiya Vladimirovna Vajn Darya Sergeevna Kudryavtsev Konstantin Viktorovich	RU2721554C1
METHOD FOR PLACENTAL MICROCIRCULATION DISORDER CORRECTION IN ADMA-LIKE GESTOSIS MODELS IN EXPERIMENT BY SINGLE ISCHEMIC EPISODE	2011	Pokrovskij Mikhail Vladimirovich Gureev Vladimir Vladimirovich Poljanskaja Oksana Sergeevna Artjushkova Elena Borisovna Korokin Mikhail Viktorovich Gudyrev Oleg Sergeevich Belous Aleksandr Sergeevich Tsybul'Skij Igor' Valer'Evich Kotel'Nikova Lilija Viktorovna Denisjuk Tat'Jana Alekseevna Terekhova Elena Gennad'Evna Babko Anna Vladimirovna Alekhin Sergej Aleksandrovich Alekhina Valerija Valer'Evna Mostovoj Aleksandr Sergeevich Lebedev Kirill Aleksandrovich Starosel'Tseva Ol'Ga Aleksandrovna Zhukov Sergej Vladimirovich Kaplin Anton Nikolaevich	RU2481103C1
METHOD FOR CORRECTION OF PLACENTAL MICROCIRCULATION DISORDER BY ARGINASE II INHIBITOR	2016	Pokrovskij Mikhail Vladimirovich Kudryavtsev Konstantin Viktorovich Pokrovskaya Tatyana Grigorevna Korokin Mikhail Viktorovich Peresypkina Anna Aleksandrovna Gureev Vladimir Vladimirovich Nikitina Vladislava Vladimirovna	RU2644271C1

RU 2 462 253 C1

Authors

Pokrovskij Mikhail Vladimirovich

Gureev Vladimir Vladimirovich

Poljanskaja Oksana Sergeevna

Artjushkova Elena Borisovna

Korokin Mikhail Viktorovich

Gudyrev Oleg Sergeevich

Bratchikov Oleg Ivanovich

Chernomortseva Elena Stanislavovna

Filimonov Vjacheslav Aleksandrovich

Belous Aleksandr Sergeevich

Tsybul'Skij Igor' Valer'Evich

Kotel'Nikova Lilija Viktorovna

Terekhova Elena Gennad'Evna

Babko Anna Vladimirovna

Alekhin Sergej Aleksandrovich

Alekhina Valerija Valer'Evna

Mostovoj Aleksandr Sergeevich

Zhernakov Evgenij Vladislavovich

Golovchenko Il'Ja Olegovich

Khadieva Taisija Abduladirovna

Pakhomov Sergej Petrovich

Dates

2012-09-27—Published

2011-08-31—Filed