FIELD: chemistry.
SUBSTANCE: invention relates to 4-[3-(4-cyclopropane carbonyl piperazine-1-carbonyl)-4-fluorobenzene)-2H-phthalazin-1-one in crystalline form A, as well as methods for production thereof and a pharmaceutical composition for inhibiting PARP based thereon. A novel form of 4-[3-(4-cyclopropane carbonyl piperazine-1-carbonyl)-4-fluorobenzene)-2H-phthalazin-1-one is obtained, which contains fewer impurities and can be used to produce high-purity pharmaceutical drug formulations.
EFFECT: fewer impurities.
12 cl, 5 dwg, 6 ex
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Authors
Dates
2012-10-27—Published
2007-10-15—Filed