FIELD: medicine.
SUBSTANCE: method for prediction of essential hypertension in females with hypertensive disorders accompanying pregnancy with a family history of cardiovascular disease at a young age and episodes of high blood pressure at random measurements in the nonpregnant state on the basis of genetic testing. Buccal epithelium is sampled to recover DNA samples subject to polymerase chain reaction. The analysis results are used to specify the information signs and to calculate a prognostic index D by formula: D=1.68×OH+0.71×ITGB3+0.60×AGTR2-0.61×ITGA2+0.56×"П"+1.53×"АГ"-2.25. If D is less than 0, no risk of developing essential arterial hypertension is stated, and if D is more than 0, a high risk of developing essential arterial hypertension is predicted.
EFFECT: higher accuracy of the prediction procedure.
3 ex
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Authors
Dates
2013-04-27—Published
2012-03-19—Filed