METHOD FOR PREDICTION OF RISK OF DEVELOPING PREECLAMPSIA WITH UNDERLYING GESTATIONAL DIABETES MELLITUS IN PATIENTS AFTER USING ASSISTED REPRODUCTIVE TECHNOLOGIES Russian patent published in 2024 - IPC G01N33/58 C12Q1/6806 C12Q1/6827 C12Q1/686 C12Q1/6883 A61B5/107 A61B17/435 

Abstract RU 2821559 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to obstetrics and gynaecology, and can be used to predict the risk of developing preeclampsia with underlying gestational diabetes mellitus in patients after using assisted reproductive technologies. Woman’s body weight index in the first trimester of pregnancy and the type of assisted reproductive technology program are determined: embryo transfer in a superovulation stimulation cycle or a thawed embryo transfer in a cryotransfer cycle, the presence of cardiovascular diseases and the genotype of the polymorphic variant of the gene ApoB Pro2739leu G > A. Obtained values are substituted into the formula for calculating the prognostic index D. At index D > 0, high risk of developing preeclampsia is predicted, with D < 0 indicates no risk of developing preeclampsia.

EFFECT: method enables predicting the risk of developing preeclampsia with underlying gestational diabetes mellitus in the patients after using assisted reproductive technologies by calculating a prognostic index.

1 cl, 2 ex

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RU 2 821 559 C1

Authors

Murzin Aleksandr Viktorovich

Melkozerova Oksana Aleksandrovna

Tretiakova Tatiana Borisovna

Bashmakova Nadezhda Vasilevna

Denisov Artem Alekseevich

Dates

2024-06-25Published

2023-12-07Filed