FIELD: biotechnologies.
SUBSTANCE: invention refers to a separation method of fractions of autoantibodies of IgG class to immunoregulatory cytokine TNF from human blood serum using a set of affine chromatography procedures and a magnetic separation procedure performed using magnetic particles covered with streptavidin, and polyclonal antibodies to TNF, which are marked with biotin.
EFFECT: obtaining pure fractions of autoantibodies to TNF of IgG class.
1 cl, 1 ex, 1 tbl
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