FIELD: medicine.
SUBSTANCE: invention refers to medicine and tissue engineering, and may be used in cardiovascular surgery for small-vessel bypasses. A vascular graft is made by two-phase electrospinning with the staged introduction of the ingredients into the polymer composition.
EFFECT: making the bioresorbed small-diameter vascular graft possessing the improved biocompatibility ensured by using the polymer composition of polyhydroxybutyrate (PHBV) with oxyvalerate, and epsilon-polycaprolactone with type IV collagen, human fibronectin and human fibroblast growth factor (hFGF) additionally introduced into the composition.
2 cl, 1 ex
Title | Year | Author | Number |
---|---|---|---|
TISSUE-ENGINEERING BIODEGRADABLE VASCULAR IMPLANT | 2016 |
|
RU2642259C2 |
TECHNOLOGY OF PRODUCING FUNCTIONALLY ACTIVE BIODEGRADABLE SMALL-DIAMETER VASCULAR PROSTHESES WITH DRUG COATING | 2019 |
|
RU2702239C1 |
METHOD FOR IN VITRO PRODUCTION OF A PERSONALIZED CELL-POPULATED VASCULAR PROSTHESIS | 2021 |
|
RU2764051C1 |
TISSUE-ENGINEERED SMALL-DIAMETER VASCULAR GRAFT AND METHOD FOR MAKING IT | 2012 |
|
RU2496526C1 |
METHOD OF MANUFACTURE OF BIODEGRADABLE VASCULAR GRAFTS OF SMALL DIAMETER WITH MODIFIED SURFACE | 2018 |
|
RU2675269C1 |
METHOD FOR PRODUCING A MICROFIBER MATERIAL RELEASING MEDICAMENT | 2017 |
|
RU2669344C1 |
METHOD FOR MANUFACTURE OF MATERIAL FOR TISSUE-ENGINEERING STRUCTURES AND FORMING SOLUTION FOR ITS IMPLEMENTATION | 2015 |
|
RU2622986C2 |
METHOD FOR PRODUCING SMALL-DIAMETER LOW-POROSITY VASCULAR PROSTHESES (VERSIONS) | 2014 |
|
RU2572333C1 |
FUNCTIONALLY ACTIVE BIODEGRADABLE VASCULAR PATCH FOR ARTERIAL RECONSTRUCTION | 2019 |
|
RU2707964C1 |
METHOD FOR PREPARING BIODEGRADABLE MEMBRANES FOR PREVENTING ADHESION FORMATION FOLLOWING CARDIOSURGICAL OPERATIONS | 2013 |
|
RU2525181C1 |
Authors
Dates
2014-01-20—Published
2012-11-21—Filed