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2 505 536

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IPC

C07D295/155(2006-01-01)

A61K31/5375(2006-01-01)

A61P25/24(2006-01-01)

(21) (22)

Application

2012158090/04, 2012-12-29

(24)

Start date

2012-12-29

(22)

Actual filing date

2012-12-29

(45)

Published

2014-01-27

(72)

Inventor

Kamkina Natalija VladimirovnaKrasnikov Sergej VladislavovichPunegova Natalija Vasil'EvnaKustov Artem Andreevich

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Tekhnicheskij Universitet"

4-(1-HYDROXY-1-METHYL-2-MORPHOLINOETHYL)BENZOIC AND 4-(1-HYDROXY-2-MORPHOLINOCYCLOHEXYL)BENZOIC ACIDS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, ESTERS, POSSESSING ANXIOLYTIC ACTIVITY, AND METHOD OF OBTAINING THEREOF Russian patent published in 2014 - IPC C07D295/155 A61K31/5375 A61P25/24

Abstract RU 2505536 C1

FIELD: chemistry.

SUBSTANCE: invention relates to tranquilising compounds, contributing to reduction of anxiety, increase of cognitive and motor activity, namely to 4-(1-hydroxy-1-methyl-2-morpholinoethyl)benzoic acid (1) and 4-(1-hydroxy-2-morpholinocyclohexyl)benzoic acid (2), their pharmaceutically acceptable salts and esters. In addition, object of invention is also presented by method of obtaining and compounds.

EFFECT: compounds, possessing anxiolytic activity, which do not manifest considerable sedative action, hypotension and excitatory action on central nervous system.

2 cl, 3 tbl

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RU 2 505 536 C1

Authors

Kamkina Natalija Vladimirovna

Krasnikov Sergej Vladislavovich

Punegova Natalija Vasil'Evna

Kustov Artem Andreevich

Dates

2014-01-27—Published

2012-12-29—Filed