FIELD: medicine.
SUBSTANCE: present invention refers to medicine, namely to medical genetics and psychiatry, and may be used for the prediction of a risk of paranoid schizophrenia. Substance of the method: DNA is recovered by phenol-chloroform extraction that is followed by genetic typing of polymorphous locus rs 1443445 of NTRK2 gene, locus rs 1946698, locus rs 7170062, locus rs 11631508 of NTRK3 gene, locus rs 1469794 of NRXN1 gene; if observing the genetic type NTRK2*C/*C (rs 1443445), the genetic type NTRK3*G/*G (rs 1946698), the genetic type NTRK3*T7*T (rs 7170062), the genetic type NTRK3*A/*A (rs 11631508) in Russian people; the genetic type NRXN1*A/*A (rs 1469794) in the Tatar people, the risk of paranoid schizophrenia is predicted.
EFFECT: using the invention enables the more accurate, objective prediction of the disease.
1 tbl, 2 ex, 5 dwg
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RU2505608C1 |
