METHOD OF PREDICTING OPEN-ANGLE GLAUCOMA IN PATIENTS WITH EYE MANIFESTATIONS OF PSEUDOEXFOLIATION SYNDROME Russian patent published in 2014 - IPC A61B3/13 A61B5/00 

Abstract RU 2508043 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to ophthalmology. To predict development of open-angle glaucoma (OAG), eye parameters are assessed in patients with eye manifestations of pseudoexfoliation syndrome (PES). PES stage on eye is determined; thickness of crystalline lens is measured, patient's age and presence or absence of artherosclerosis, ischemic heart disease, chronic failure of brain vessels, hypertension disease are registered. After that, index of risk of open-angle glaucoma development (IRD) is calculated by formula: IRD=0.0035*AGE+0.173*PES+0.094*CR+0.528*AT+0.377*IHD+0.276*CFBV+. 0.388*HT-0.322, where AGE is patient's age, years, PES is stage of PES (from 1 to 3), CR is crystalline lens thickness in mm, presence - 1, absence - 0 of accompanying cardiovascular diseases: AT - artherosclerosis, IHD - ischemic heart disease, CFBV - chronic failure of brain vessels, HD - hypertension disease, 0,322 is an independent constant If IRD>2, development of open-angle glaucoma on eyes with PES manifestations is predicted.

EFFECT: method makes it possible to predict risk of OAG development on eyes with clinical PES signs, taking into account PES stage, crystalline lens thickness, age and presence of cardiovascular diseases.

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RU 2 508 043 C1

Authors

Agafonova Viktorija Veniaminovna

Frankovska-Gerlak Malgozhata

Brizhak Polina Evgen'Evna

Bessarabov Anatolij Nikitich

Dates

2014-02-27Published

2012-12-20Filed